The biomarker and therapeutic potential of circular Rnas in Schizophrenia

A Nedoluzhko, N Gruzdeva, F Sharko, S Rastorguev… - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) are endogenous, single-stranded, most frequently non-coding
RNA (ncRNA) molecules that play a significant role in gene expression regulation. Circular …

Meta-analysis of brain samples of individuals with schizophrenia detects down-regulation of multiple ATP synthase encoding genes in both females and males

NK Shroitman, A Yitzhaky, DB Shachar… - Journal of Psychiatric …, 2023 - Elsevier
Schizophrenia is a chronic and debilitating mental disorder, with unknown pathophysiology.
Converging lines of evidence suggest that mitochondrial functioning may be compromised …

Lower levels of soluble β-amyloid precursor protein, but not β-amyloid, in the frontal cortex in schizophrenia

B Dean, J Duce, QX Li, CL Masters, E Scarr - Psychiatry Research, 2024 - Elsevier
We identified a sub-group (25%) of people with schizophrenia (muscarinic receptor deficit
schizophrenia (MRDS)) that are characterised because of markedly lower levels of cortical …

Transcriptomic Data Analysis Reveals a Down-Expression of Galectin-8 in Schizophrenia Hippocampus

MC Petralia, R Ciurleo, A Bramanti, P Bramanti… - Brain Sciences, 2021 - mdpi.com
Schizophrenia (SCZ) is a severe psychiatric disorder with several clinical manifestations that
include cognitive dysfunction, decline in motivation, and psychosis. Current standards of …

Identification of a hypoxia-related signature as candidate detector for schizophrenia based on genome-wide gene expression

Z Li, X Sun, J He, D Kong, J Wang, L Wang - Human Heredity, 2023 - karger.com
Abstract Introduction: Schizophrenia (SCZ), a severe neuropsychiatric disorder with high
genetic susceptibility, has high rates of misdiagnosis due to the unavoidably subjective …

Altered resting-state functional connectivity in hiPSCs-derived neuronal networks from schizophrenia patients

S Puvogel, K Blanchard, BS Casas, RL Miller… - Frontiers in Cell and …, 2022 - frontiersin.org
Schizophrenia (SZ) is a severe mental disorder that arises from abnormal
neurodevelopment, caused by genetic and environmental factors. SZ often involves …

[HTML][HTML] Methylome-wide association study of patients with recent-onset psychosis

YH Piao, Y Cui, FZ Rami, L Li… - Clinical …, 2022 - ncbi.nlm.nih.gov
Objective Dysregulation of gene expression through epigenetic mechanisms may have a
vital role in the pathogenesis of schizophrenia (SZ). In this study, we investigated the …

Integrated bioinformatic analysis for the identification of potential biomarkers of kidney damage in hyperoxaluria

U Adiga, S Adiga, TM Desy, N Honnalli… - Journal of Applied …, 2024 - japsonline.com
Hyperoxaluria is described by an augmented urinary elimination of oxalate. Systemic
oxalosis is the term for the condition that occurs when the burden of calcium oxalate (CaOx) …

Analysis of nerve growth factor (NGF) gene methylation in patients with schizophrenia

A Charkaneh, Z Salehi, HS Rad, R Soleimani… - Gene Reports, 2023 - Elsevier
According to the neurotrophin hypothesis, schizophrenia can be caused by neurotrophic
factors. One of these neurotrophic factors is the nerve growth factor (NGF), which has a …

Neurodevelopment, brain vasculature and schizophrenia

SP Lütjens - 2023 - research.rug.nl
Schizophrenia is a mental disorder that arises from abnormal neurodevelopment, led by
genetic and environmental factors. Several lines of evidence suggest the involvement of …