Rhinovirus has been neglected in the past because it was generally perceived as a
respiratory virus only capable of causing mild common cold. Contemporary epidemiological …

The PIM Kinases belong to the family of a proto-oncogene that essentially phosphorylates
the serine/threonine residues of the target proteins. They are primarily categorized into three …

Background The prevalence of age-associated diseases, such as chronic obstructive
pulmonary disease (COPD), is increasing as the average life expectancy increases around …

The human nasal epithelium contains basal stem/progenitor cells that produce differentiated
multiciliated and mucosecretory progeny. Basal epithelial cells can be expanded in cell …

Despite advances in the treatment of asthma, optimization of symptom control remains an
unmet need in many patients. These patients, labeled severe asthma, are responsible for a …

The proviral integration for the Moloney murine leukemia virus (PIM) kinases, belonging to
serine/threonine kinase family, have been found to be overexpressed in various types of …

PIM kinase is involved in the cellular processes of growth, differentiation and apoptosis.
However, the role of PIM1 in lipopolysaccharide (LPS)-induced acute lung injury (ALI) …

Summary Enterovirus A71 (EV-A71) infection causes hand-foot-and-mouth disease (HFMD)
and fatal neurological diseases, and there are no effective treatments. Host factors play key …

Objective and design This observational study investigated the regulatory mechanism of Pim-
1 in inflammatory signaling pathways. Materials THP-1, RAW 264.7, BV2, and Jurkat human …

Background Serine/threonine kinase 1 (PIM1) plays a crucial role in cell growth,
differentiation, and apoptosis. However, its role in the pathogenesis of concanavalin A …