Deregulated metabolic pathways in ovarian cancer: cause and consequence

R Murali, V Balasubramaniam, S Srinivas, S Sundaram… - Metabolites, 2023 - mdpi.com
Ovarian cancers are tumors that originate from the different cells of the ovary and account for
almost 4% of all the cancers in women globally. More than 30 types of tumors have been …

Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer

S Banerjee, M Hatimuria, K Sarkar, J Das… - Chemical Research …, 2023 - ACS Publications
Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

Olaparib enhances sensitization of BRCA-proficient breast cancer cells to x-rays and protons

S Park, C Choi, H Kim, YJ Shin, Y Oh, W Park… - Breast Cancer Research …, 2024 - Springer
Purpose This study aimed to compare the radiosensitizing effect of the PARP inhibitor,
Olaparib, between proton and X-rays irradiations in BRCA-proficient breast cancer (BC) …

An optimised monophasic faecal extraction method for LC-MS analysis and its application in gastrointestinal disease

PE Kelly, HJ Ng, G Farrell, S McKirdy, RK Russell… - Metabolites, 2022 - mdpi.com
Liquid chromatography coupled with mass spectrometry (LC-MS) metabolomic approaches
are widely used to investigate underlying pathogenesis of gastrointestinal disease and …

In Vivo Chemosuppressive Effects of Kolaviron on 7,12-Dimethylbenzanthracene-Induced Mammary Lesions are Associated with Changes in Levels of Estrogen …

CO Attah, UI Alhaji, DA Ameh, GE Forcados… - Journal of Medicinal …, 2024 - liebertpub.com
Garcinia kola is a medicinal food commonly consumed in Sub-Sahara Africa, for which
Kolaviron (KV) is the active portion. As a follow-up to our earlier chemopreventive studies …

Natural compounds solasonine and alisol B23-acetate target GLI3 signaling to block oncogenesis in MED12-altered breast cancer

S Akula, CG Gonzalez, S Kermet… - Molecular Biology …, 2024 - journals.shirazu.ac.ir
Breast cancer remains to be the second leading cause of cancer deaths worldwide thereby
highlighting the critical need to find superior treatment strategies for this disease. In the …