Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use

P Chiodelli, A Bugatti, C Urbinati, M Rusnati - Molecules, 2015 - mdpi.com
Angiogenesis, the process of formation of new blood vessel from pre-existing ones, is
involved in various intertwined pathological processes including virus infection …

Pregnancy-specific glycoproteins: complex gene families regulating maternal-fetal interactions.

T Moore, GS Dveksler - International Journal of …, 2014 - search.ebscohost.com
The pregnancy-specific glycoproteins (PSGs) are the most abundant trophoblastic proteins
in maternal blood during human pregnancy and they appear to be exclusive to species with …

Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia

Y Zhou, MJ Gormley, NM Hunkapiller… - The Journal of …, 2013 - Am Soc Clin Investig
During human pregnancy, a subset of placental cytotrophoblasts (CTBs) differentiates into
cells that aggressively invade the uterus and its vasculature, anchoring the progeny and …

Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene

S Cui, M Leyva–Vega, EA Tsai, SF EauClaire… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Biliary atresia (BA) is a progressive fibroinflammatory disorder of
infants involving the extrahepatic and intrahepatic biliary tree. Its etiology is unclear but is …

Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations

T Moore, JM Williams, MA Becerra-Rodriguez… - …, 2022 - rep.bioscientifica.com
Pregnancy-specific glycoproteins (PSGs) are members of the immunoglobulin superfamily
and are closely related to the predominantly membrane-bound CEACAM proteins. PSGs are …

Medawar's PostEra: galectins emerged as key players during fetal-maternal glycoimmune adaptation

E Menkhorst, NG Than, U Jeschke… - Frontiers in …, 2021 - frontiersin.org
Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Z Huang, PF Lai, ATH Cocker… - Biochemical Society …, 2023 - portlandpress.com
Protein N-linked glycosylation is a structurally diverse post-translational modification that
stores biological information in a larger order of magnitude than other post-translational …

Interaction of pregnancy-specific glycoprotein 1 with integrin Α5β1 is a modulator of extravillous trophoblast functions

S Rattila, CE Dunk, M Im, O Grichenko, Y Zhou… - Cells, 2019 - mdpi.com
Human pregnancy-specific glycoproteins (PSGs) serve immunomodulatory and pro-
angiogenic functions during pregnancy and are mainly expressed by syncytiotrophoblast …

[HTML][HTML] Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-β and prevents dextran sodium sulfate (DSS)-induced colitis in mice

SM Blois, G Sulkowski, I Tirado-González, J Warren… - Mucosal …, 2014 - Elsevier
Transforming growth factor-βs (TGF-βs) are secreted from cells as latent complexes and the
activity of TGF-βs is controlled predominantly through activation of these complexes …

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet—fibrinogen interaction

DK Shanley, PA Kiely, K Golla, S Allen, K Martin… - PloS one, 2013 - journals.plos.org
Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members
encoded by multigene families in rodents and primates. In human pregnancy, PSGs are …