Fear conditioning and fear extinction are Pavlovian conditioning paradigms extensively
used to study the mechanisms that underlie learning and memory formation. The neural …

Fear memory is a motivational system essential for organisms survival having a central role
in organization of defensive behaviors to threat. In the last years there has been a growing …

Pain perception is essential for survival and can be amplified or suppressed by
expectations, experiences, and context. The neural mechanisms underlying bidirectional …

Food palatability is one of many factors that drives food consumption, and the hedonic drive
to feed is a key contributor to obesity and binge eating. In this study, we identified a …

The spino-ponto-amygdaloid pathway is a major ascending circuit relaying nociceptive
information from the spinal cord to the brain. Potentiation of excitatory synaptic transmission …

Key points The central nucleus of the amygdala (CeA) encompasses the main output
pathways of the amygdala, a temporal lobe structure essential in affective and cognitive …

Network activity in the lateral central amygdala (CeL) plays a crucial role in fear learning and
emotional processing. However, the local circuits of the CeL are not fully understood and …

The central extended amygdala (EAc) is a forebrain macrosystem which has been widely
implicated in reward, fear, anxiety, and pain. Its two key structures, the lateral bed nucleus of …

Central amygdala (CeA) neurons expressing protein kinase Cδ (PKCδ+) or somatostatin
(Som+) differentially modulate diverse behaviors. The underlying features supporting cell …

A large majority of neurons in the superficial layer of the dorsal horn projects to the lateral
parabrachial nucleus (LPB). LPB neurons then project to the capsular part of the central …