[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Liposomes as biocompatible and smart delivery systems–The current state

M Dymek, E Sikora - Advances in Colloid and Interface Science, 2022 - Elsevier
Liposomes are self-assembled, closed spherical systems with a lipid bilayer, composed of ia
one or more amphiphilic phospholipids, and widely used in the pharmaceutical, cosmetic …

[HTML][HTML] Advances in oral drug delivery for regional targeting in the gastrointestinal tract-influence of physiological, pathophysiological and pharmaceutical factors

S Hua - Frontiers in pharmacology, 2020 - frontiersin.org
The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …

[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

Q Zhu, Z Chen, PK Paul, Y Lu, W Wu, J Qi - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …

[HTML][HTML] Adapting liposomes for oral drug delivery

H He, Y Lu, J Qi, Q Zhu, Z Chen, W Wu - Acta pharmaceutica sinica B, 2019 - Elsevier
Liposomes mimic natural cell membranes and have long been investigated as drug carriers
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …

Surface modification of lipid-based nanoparticles

Y Xu, T Fourniols, Y Labrak, V Préat, A Beloqui… - ACS …, 2022 - ACS Publications
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

New developments in liposomal drug delivery

BS Pattni, VV Chupin, VP Torchilin - Chemical reviews, 2015 - ACS Publications
New Developments in Liposomal Drug Delivery | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Blank image Log In Chemical Reviews ACS Publications. Most …

[HTML][HTML] Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches

DJ Brayden, TA Hill, DP Fairlie, S Maher… - Advanced drug delivery …, 2020 - Elsevier
In its 33 years, ADDR has published regularly on the po5tential of oral delivery of biologics
especially peptides and proteins. In the intervening period, analysis of the preclinical and …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Overcoming the intestinal barrier: a look into targeting approaches for improved oral drug delivery systems

Y Xu, N Shrestha, V Préat, A Beloqui - Journal of controlled release, 2020 - Elsevier
Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …