Applying CRISPR-Cas9 screens to dissect hematological malignancies
DN Iyer, AD Schimmer, H Chang - Blood Advances, 2023 - ashpublications.org
Bit by bit, over the last few decades, functional genomic tools have been piecing together the
molecular puzzle driving tumorigenesis in human patients. Nevertheless, our understanding …
molecular puzzle driving tumorigenesis in human patients. Nevertheless, our understanding …
[HTML][HTML] Application and research progress of single cell sequencing technology in leukemia
D Xie, B An, M Yang, L Wang, M Guo, H Luo… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Leukemia is a malignant tumor with high heterogeneity and a complex evolutionary process.
It is difficult to resolve the heterogeneity and clonal evolution of leukemia cells by applying …
It is difficult to resolve the heterogeneity and clonal evolution of leukemia cells by applying …
[HTML][HTML] CTDSPL2 promotes the progression of non-small lung cancer through PI3K/AKT signaling via JAK1
M Li, L Chen, F Yu, H Mei, X Ma, K Ding, Y Yang… - Cell Death …, 2024 - nature.com
Carboxy-terminal domain small phosphatase like 2 (CTDSPL2), one of the haloacid
dehalogenase phosphatases, is associated with several diseases including cancer …
dehalogenase phosphatases, is associated with several diseases including cancer …
CTDSPL2 promotes the progression of non-small lung cancer through PI3K/AKT signaling via JAK1
Z Rong, M Li, L Chen, F Yu, H Mei, X Ma, K Ding… - 2024 - researchsquare.com
Carboxy-terminal domain small phosphatase like 2 (CTDSPL2), one of the haloacid
dehalogenase phosphatases, is associated with several diseases including cancer …
dehalogenase phosphatases, is associated with several diseases including cancer …
Understanding Lineage Dependencies in Rhabdomyosarcoma
C Cleary - 2023 - search.proquest.com
Rhabdomyosarcoma (RMS) is the most common extra-cranial solid tumor in the pediatric
population of the United States by incidence. RMS is a high-grade neoplasm composed of …
population of the United States by incidence. RMS is a high-grade neoplasm composed of …
TAZ and YAP dysregulation in sarcomas
KC Garcia - 2022 - search.proquest.com
Sarcomas are comprised of a diverse group of cancers with over 50 histological types, which
are difficult to treat. In addition to lack of medical therapies, the mechanisms that drive …
are difficult to treat. In addition to lack of medical therapies, the mechanisms that drive …