The potential for improving cardio-renal outcomes by sodium-glucose co-transporter-2 inhibition in people with chronic kidney disease: a rationale for the EMPA …

WG Herrington, D Preiss, R Haynes… - Clinical kidney …, 2018 - academic.oup.com
Diabetes is a common cause of chronic kidney disease (CKD), but in aggregate, non-
diabetic diseases account for a higher proportion of cases of CKD than diabetes in many …

Early chronic kidney disease: diagnosis, management and models of care

OJ Wouters, DJ O'donoghue, J Ritchie… - Nature Reviews …, 2015 - nature.com
Chronic kidney disease (CKD) is prevalent in many countries, and the costs associated with
the care of patients with end-stage renal disease (ESRD) are estimated to exceed US $1 …

Design, recruitment, and baseline characteristics of the EMPA-KIDNEY trial

Nephrology Dialysis Transplantation, 2022 - academic.oup.com
Background The effects of the sodium-glucose co-transporter 2 inhibitor empagliflozin on
renal and cardiovascular disease have not been tested in a dedicated population of people …

[HTML][HTML] CKD progression and mortality among men and women: a nationwide study in Sweden

O Swartling, H Rydell, M Stendahl, M Segelmark… - American Journal of …, 2021 - Elsevier
Rationale & Objective Chronic kidney disease (CKD) is a global health problem with
increasing prevalence. Several sex-specific differences have been reported for disease …

[HTML][HTML] Prevalence and risk factors for CKD: a comparison between the adult populations in China and the United States

F Wang, K He, J Wang, MH Zhao, Y Li, L Zhang… - Kidney international …, 2018 - Elsevier
Introduction Chronic kidney disease (CKD) is an important noncommunicable disease
globally. Overall prevalence of CKD and distribution of its stages differ between countries …

Contribution of predictive and prognostic biomarkers to clinical research on chronic kidney disease

M Provenzano, S Rotundo, P Chiodini… - International Journal of …, 2020 - mdpi.com
Chronic kidney disease (CKD), defined as the presence of albuminuria and/or reduction in
estimated glomerular filtration rate (eGFR)< 60 mL/min/1.73 m2, is considered a growing …

Age differences in the relationships between risk factors and loss of kidney function: a general population cohort study

T Toyama, K Kitagawa, M Oshima, S Kitajima, A Hara… - BMC nephrology, 2020 - Springer
Background Annual decline in kidney function is a widely applied surrogate outcome of
renal failure. It is important to understand the relationships between known risk factors and …

Independent role of underlying kidney disease on renal prognosis of patients with chronic kidney disease under nephrology care

L De Nicola, M Provenzano, P Chiodini, S Borrelli… - PloS one, 2015 - journals.plos.org
Primary kidney disease is suggested to affect renal prognosis of CKD patients; however,
whether nephrology care modifies this association is unknown. We studied patients with …

High alcohol consumption and the risk of renal damage: a systematic review and meta-analysis

W Cheungpasitporn, C Thongprayoon… - … Journal of Medicine, 2015 - academic.oup.com
Background: The risk of renal damage in patients with high alcohol consumption is
controversial. The objective of this meta-analysis was to evaluate the associations between …

What every clinician needs to know about chronic kidney disease: Detection, classification and epidemiology

NM Selby, MW Taal - Diabetes, Obesity and Metabolism, 2024 - Wiley Online Library
Chronic kidney disease (CKD) is a major healthcare challenge, affecting> 800 million
people worldwide. Implications for population health result from the strong associations of …