Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Catalytic hairpin assembly (CHA) with advantages of high efficiency, flexible design, and
mild reaction condition is considered a promising molecular amplifier. Modified working …

The development of nanotechnology promotes the progress of analytical methods,
especially gold nanomaterials, which have attracted much interest due to their unique …

As an enzyme-free signal amplification strategy, catalytic hairpin assembly (CHA) presents
the advantages of flexible design and high efficiency. Combined with various signal output …

The circulating tumor DNA (ctDNA) is a crucial cancer marker, its sensitive monitoring is
useful for early diagnose and therapy of tumor-related diseases. Herein, a bipedal DNA …

Catalytic hairpin assembly (CHA) appears to be a particularly appealing nucleic acid circuit
because of its powerful amplification capability, simple protocols, and enzyme-free and …

DNA methylation as one of the most important epigenetic modifications has a critical role in
regulating gene expression and drug resistance in treating diseases such as cancer …

The overuse of kanamycin (KAN) has posed a significant threat to food safety. There has
been a growing concern about using gold nanoparticle (AuNP)-based aptasensors for the …

Precise evaluation of telomerase activity is highly crucial for early cancer diagnosis. In this
study, a sensitive catalytic hairpin assembly–dynamic light scattering (CHA–DLS) assay for …