Contrast-enhanced ultrasound quantification: From kinetic modeling to machine learning

S Turco, P Frinking, R Wildeboer, M Arditi… - Ultrasound in medicine …, 2020 - Elsevier
Ultrasound contrast agents (UCAs) have opened up immense diagnostic possibilities by
combined use of indicator dilution principles and dynamic contrast-enhanced ultrasound …

New quantification methods for carotid intra-plaque neovascularization using contrast-enhanced ultrasound

Z Akkus, A Hoogi, G Renaud, SCH van den Oord… - Ultrasound in medicine …, 2014 - Elsevier
As carotid intra-plaque neovascularization (IPN) is linked to progressive atherosclerotic
disease and plaque vulnerability, its accurate quantification might allow early detection of …

Quantitative contrast-enhanced ultrasound of intraplaque neovascularization in patients with carotid atherosclerosis

SCH van den Oord, Z Akkus, JG Bosch… - Ultraschall in der …, 2015 - thieme-connect.com
Purpose: Intraplaque neovascularization (IPN) is an increasingly studied marker of the
vulnerable atherosclerotic plaque, and contrast-enhanced ultrasound (CEUS) is an in vivo …

Lumen segmentation and motion estimation in B-mode and contrast-enhanced ultrasound images of the carotid artery in patients with atherosclerotic plaque

DDB Carvalho, Z Akkus… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
In standard B-mode ultrasound (BMUS), segmentation of the lumen of atherosclerotic carotid
arteries and studying the lumen geometry over time are difficult owing to irregular lumen …

Fully automated segmentation of bladder sac and measurement of detrusor wall thickness from transabdominal ultrasound images

Z Akkus, BH Kim, R Nayak, A Gregory, A Alizad… - Sensors, 2020 - mdpi.com
Ultrasound measurements of detrusor muscle thickness have been proposed as a
diagnostic biomarker in patients with bladder overactivity and voiding dysfunction. In this …

Fully automated carotid plaque segmentation in combined contrast-enhanced and B-mode ultrasound

Z Akkus, DDB Carvalho, SCH van den Oord… - Ultrasound in medicine …, 2015 - Elsevier
Carotid plaque segmentation in B-mode ultrasound (BMUS) and contrast-enhanced
ultrasound (CEUS) is crucial to the assessment of plaque morphology and composition …

Carotid intraplaque neovascularization quantification software (CINQS)

Z Akkus, G Van Burken… - IEEE journal of …, 2014 - ieeexplore.ieee.org
Intraplaque neovascularization (IPN) is an important biomarker of atherosclerotic plaque
vulnerability. As IPN can be detected by contrast enhanced ultrasound (CEUS), imaging …

Quantification of bound microbubbles in ultrasound molecular imaging

V Daeichin, Z Akkus, I Skachkov… - IEEE transactions on …, 2015 - ieeexplore.ieee.org
Molecular markers associated with diseases can be visualized and quantified noninvasively
with targeted ultrasound contrast agent (t-UCA) consisting of microbubbles (MBs) that can …

Statistical segmentation of carotid plaque neovascularization

Z Akkus, JG Bosch… - Medical Imaging …, 2013 - spiedigitallibrary.org
In several studies, intraplaque neovascularization (IPN) has been linked with plaque
vulnerability. The recent development of contrast enhanced ultrasound enables IPN …

New quantification methods for carotid intraplaque neovascularization in contrast enhanced ultrasound

Z Akkus, G Renaud, N De Jong… - 2013 IEEE …, 2013 - ieeexplore.ieee.org
Carotid intraplaque neovascularization (IPN) has been associated with progressive
atherosclerotic disease and plaque vulnerability. Therefore, its accurate quantification might …