Unlocking the potential of TRPV1 based siRNA therapeutics for the treatment of chemotherapy-induced neuropathic pain
Chemotherapy-induced neuropathic pain (CINP) is among the most common clinical
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …
Bioactive compounds for neuropathic pain: An update on preclinical studies and future perspectives
Among different types of chronic pain, neuropathic pain (NP), arising from damage to the
nervous system, including peripheral fibers and central neurons, is notoriously difficult to …
nervous system, including peripheral fibers and central neurons, is notoriously difficult to …
[HTML][HTML] The anti-inflammatory and antioxidant effects of sodium propionate
A Filippone, M Lanza, M Campolo, G Casili… - International journal of …, 2020 - mdpi.com
The major end-products of dietary fiber fermentation by gut microbiota are the short-chain
fatty acids (SCFAs) acetate, propionate, and butyrate, which have been shown to modulate …
fatty acids (SCFAs) acetate, propionate, and butyrate, which have been shown to modulate …
Dietary supplementation of gingerols-and shogaols-enriched ginger root extract attenuate pain-associated behaviors while modulating gut microbiota and metabolites …
Neuroinflammation is a central factor in neuropathic pain (NP). Ginger is a promising
bioactive compound in NP management due to its anti-inflammatory property. Emerging …
bioactive compound in NP management due to its anti-inflammatory property. Emerging …
[HTML][HTML] Nutraceuticals: A source of benefaction for neuropathic pain and fibromyalgia
Though both neuropathy and fibromyalgia are serious complications that cause widespread
pain, distinguishing between the two in order to provide adequate care is difficult. Metabolic …
pain, distinguishing between the two in order to provide adequate care is difficult. Metabolic …
[HTML][HTML] Zerumbone ameliorates neuropathic pain symptoms via cannabinoid and PPAR receptors using in vivo and in silico models
Neuropathic pain is a chronic pain condition persisting past the presence of any noxious
stimulus or inflammation. Zerumbone, of the Zingiber zerumbet ginger plant, has exhibited …
stimulus or inflammation. Zerumbone, of the Zingiber zerumbet ginger plant, has exhibited …
Sida cordifolia L. attenuates behavioral hypersensitivity by interfering with KIF17-NR2B signaling in rat model of neuropathic pain
V Tiwari, S Hemalatha - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Sida cordifolia L., a perennial subshrub belonging to the
Malvaceae family, holds noteworthy significance in the Indian Ayurvedic System and global …
Malvaceae family, holds noteworthy significance in the Indian Ayurvedic System and global …
Downregulation of TRPM7, TRPM8, and TRPV1 channels modulate apoptotic parameters and neurodegenerative markers: Focus on neuronal differentiation and …
The transient receptor potential channel (TRP) channels are expressed in neuronal tissues
and involved in neurological diseases such as pain, epilepsy, neuronal apoptosis, and …
and involved in neurological diseases such as pain, epilepsy, neuronal apoptosis, and …
Bergenin ameliorates chemotherapy-induced neuropathic pain in rats by modulating TRPA1/TRPV1/NR2B signalling
Chemotherapy-induced neuropathic pain (CINP) is one of the most prominent and
incapacitating complication associated with chemotherapeutic regimens. The exact …
incapacitating complication associated with chemotherapeutic regimens. The exact …
Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine‐Induced Neuropathic Pain
P Xi, R Mao, S Wu, L Liu, C Cai, L Lu… - Mediators of …, 2022 - Wiley Online Library
Background. Polydatin (PD) is the primary active compound in Polygonum cuspidatum Sieb
and has been demonstrated to exert anti‐inflammatory and neuroprotective activities. In the …
and has been demonstrated to exert anti‐inflammatory and neuroprotective activities. In the …