Innovative three-dimensional models for understanding mechanisms underlying lung diseases: powerful tools for translational research

M Nizamoglu, MM Joglekar, CR Almeida… - European …, 2023 - Eur Respiratory Soc
Chronic lung diseases result from alteration and/or destruction of lung tissue, inevitably
causing decreased breathing capacity and quality of life for patients. While animal models …

Alveolus lung-on-a-chip platform: a proposal

N Campillo, VR Oliveira, RK da Palma - Chemosensors, 2021 - mdpi.com
Respiratory diseases are top-ranked causes of deaths and disabilities around the world,
making new approaches to the treatment necessary. In recent years, lung-on-a-chip …

Unveiling Mechanobiology: A Compact Device for Uniaxial Mechanical Stimulation on Nanofiber Substrates and Its Impact on Cellular Behavior and Nanoparticle …

S Basak, A Tiwari, D Sharma… - ACS Applied Bio …, 2024 - ACS Publications
Biotechnology and its allied sectors, such as tissue culture, regenerative medicine, and
personalized medicine, primarily rely upon extensive studies on cellular behavior and their …

Revolutionizing respiratory health research:“commercially-available lung-on-a-chip and air-liquid interface systems”

S Park, CG Woo, YJ Cho - Frontiers in Lab on a Chip Technologies, 2024 - frontiersin.org
Inhalation of ultrafine particles, aerosol contaminants, and cigarette smoke can induce
respiratory diseases. As humans are constantly exposed to various exogenous substances …

Culture and Co-culture of Cells for Multi-organ on a Chip

A Arathi, X Joseph, KB Megha, V Akhil… - Microfluidics and Multi …, 2022 - Springer
The pre-clinical trials in the drug discovery timeline involve an immense amount of time and
money to elucidate the drug responses precisely. Cell culture techniques have been utilized …

[PDF][PDF] Applications of Nanofiber Membranes in Microphysiological Systems

P Kanabekova, A Martin, A Kemelbekova… - 2022 - scholar.archive.org
Microfluidic organs-on-chips or microphysiological systems (MPS) are promising tools that
can potentially replace animal testing in drug development. MPS are platforms with …

Lung-on-chip

AM van der Does, OT Guenat, T Geiser… - 3D Lung Models for …, 2022 - Elsevier
An increasing collection of cell culture techniques is currently available to model the lung
microenvironment and study lung diseases, tissue, and tissue regeneration. In this chapter …

Design of a Pulsatile Air Flow Modulation Device for a Lung-on-a-Chip

B Ng - 2022 - escholarship.mcgill.ca
Recent studies have demonstrated the feasibility of recapitulating human lung organ
physiology in a lung-on-a-chip (LOC). To model the lung specifically, the key forces required …