There are two major challenges in the current high throughput screening drug design: the
large number of descriptors which may also have autocorrelations and, proper parameter …

One of the potential threats to public health microbiology in 21st century is the increased
mortality rate caused by Zika virus (ZIKV), a mosquito-borne flavivirus. The severity of ZIKV …

Background: Viruses are the most devastating pathogens of almost all life forms including
humans and animals. Viruses can replicate very fast and may affect any metabolic and …

CXCR4 is involved in inflammation, cancer metastasis and also HIV-1 entry into immune
host cells. In the present research, it was decided to investigate the efficacy of some CXCR4 …

Since the beginning of the century, viral infection has become a widespread problem to
public health globally. Recently, the latest newcomer of the Flaviviridae family, the Zika virus …

Introduction: After the WHO declared Zika virus (ZIKV) as a public health emergency of
international concern, intense research for the development of vaccines and drugs has been …

Zika virus is a mosquito transmitted lavivirus belongs to family Flaviviridae which became
the focus of an ongoing pandemic and public health emergency all around the world. It is …

Zika virus (ZIKV) remained a comparatively incomprehensible animal virus to us so far.
During a recent series of outbreaks with severe clinical complications, this virus came into …

Anticancer drugs are defined as drugs which are used for treating of cancer. Cancer can be
diagnosed by different methods. Cancer can be cured by anticancer drugs like bone marrow …

Heterocycles are present in the structure of many biological active compounds and
marketed drugs. Diazepine ring system (Figure-1) is one of the most important members of …