Nicotinamide in Combination with EGFR-TKIs for the Treatment of Stage IV Lung Adenocarcinoma with EGFR Mutations: A Randomized Double-Blind (Phase IIb) Trial
HJ Oh, SC Bae, IJ Oh, CK Park, KM Jung, DM Kim… - Clinical Cancer …, 2024 - AACR
Purpose: RUNX3 is a tumor suppressor gene, which is inactivated in approximately 70% of
lung adenocarcinomas. Nicotinamide, a sirtuin inhibitor, has demonstrated potential in re …
lung adenocarcinomas. Nicotinamide, a sirtuin inhibitor, has demonstrated potential in re …