Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19
AB Koopmans, MH Braakman, DJ Vinkers… - Translational …, 2021 - nature.com
Extensive migration has led to the necessity of knowledge regarding the treatment of
migrants with different ethnical backgrounds. This is especially relevant for pharmacological …
migrants with different ethnical backgrounds. This is especially relevant for pharmacological …
Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling
G Magliocco, F Rodieux, J Desmeules, CF Samer… - Pediatric …, 2020 - nature.com
The activity of drug-metabolizing enzymes (DME) shows high inter-and intra-individual
variability. Genetic polymorphisms, exposure to drugs, and environmental toxins are known …
variability. Genetic polymorphisms, exposure to drugs, and environmental toxins are known …
Gene Polymorphisms and Drug–Drug Interactions Determine the Metabolic Profile of Blonanserin
F Ye, X Li, J Ni, X Xu, J Luo, Y Zhong, Y Wang… - … of Pharmacology and …, 2024 - ASPET
This study aimed to evaluate the effects of cytochrome P450 3A4 (CYP3A4) gene
polymorphism and drug interaction on the metabolism of blonanserin. Human recombinant …
polymorphism and drug interaction on the metabolism of blonanserin. Human recombinant …