Autophagy, a main intracellular catabolic process, is induced in response to a variety of
cellular stresses to promptly degrade harmful agents and to coordinate the activity of …

Mitochondrial dysfunction and stem cell exhaustion are two hallmarks of aging. In the
hematopoietic system, aging is linked to imbalanced immune response and reduced …

Autophagy is a very well-coordinated intracellular process that maintains cellular
homeostasis under basal conditions by removing unnecessary or dysfunctional components …

Background The impact of global overconsumption of simple sugars on bone health, which
peaks in adolescence/early adulthood and correlates with osteoporosis (OP) and fracture …

Several factors, such as ischemia, infection and skin injury impair the wound healing
process. One common pathway in all these processes is related to the reactive oxygen …

Citrate, generated in the mitochondria, is a key metabolite that might link metabolism with
signaling, chromatin structure and transcription to orchestrate mesenchymal stem cells …

The promyelocytic leukemia protein (PML) is the core organizer of cognate nuclear bodies
(PML-NBs). Through physical interaction or modification of diverse protein clients, PML-NBs …

This book introduces charnolophagy (CP) as energy-driven, lysosomal-dependent
mitochondrial inclusion-specific pleomorphic Charnoly body (CB) autophagy (ATG) …

Ο καρκίνος του μαστού είναι μια ετερογενής ασθένεια που αποτελεί τον πιο συχνά
εμφανιζόμενο καρκίνο στις γυναίκες ετησίως. Η Ετερογένεια αφορά την προέλευση των …

Increased recruitment of new adipocytes from mesenchymal sources, such as mesenchymal
stem cells (MSCs), serves as one of the major causes of excessive adipose tissue formation …