[HTML][HTML] Microemulsions and nanoemulsions in skin drug delivery

EB Souto, A Cano, C Martins-Gomes, TE Coutinho… - Bioengineering, 2022 - mdpi.com
Microemulsions and nanoemulsions are lipid-based pharmaceutical systems with a high
potential to increase the permeation of drugs through the skin. Although being isotropic …

[HTML][HTML] Nanotechnology: a promising approach for delivery of neuroprotective drugs

S Naqvi, A Panghal, SJS Flora - Frontiers in Neuroscience, 2020 - frontiersin.org
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

[HTML][HTML] Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics

YH Choi, HK Han - Journal of pharmaceutical investigation, 2018 - Springer
Nanomedicines have evolved into various forms including dendrimers, nanocrystals,
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …

[HTML][HTML] Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Strategies to address low drug solubility in discovery and development

HD Williams, NL Trevaskis, SA Charman… - Pharmacological …, 2013 - ASPET
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

50 years of oral lipid-based formulations: provenance, progress and future perspectives

OM Feeney, MF Crum, CL McEvoy, NL Trevaskis… - Advanced drug delivery …, 2016 - Elsevier
Lipid based formulations (LBF) provide well proven opportunities to enhance the oral
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …

Nanodrugs: pharmacokinetics and safety

S Onoue, S Yamada, HK Chan - International journal of …, 2014 - Taylor & Francis
To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …

In vitro models for the prediction of in vivo performance of oral dosage forms

ES Kostewicz, B Abrahamsson, M Brewster… - European Journal of …, 2014 - Elsevier
Accurate prediction of the in vivo biopharmaceutical performance of oral drug formulations is
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …

Lipid-based formulations for oral administration of poorly water-soluble drugs

H Mu, R Holm, A Müllertz - International journal of pharmaceutics, 2013 - Elsevier
Lipid-based drug delivery systems have shown great potentials in oral delivery of poorly
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …