[HTML][HTML] Microemulsions and nanoemulsions in skin drug delivery
Microemulsions and nanoemulsions are lipid-based pharmaceutical systems with a high
potential to increase the permeation of drugs through the skin. Although being isotropic …
potential to increase the permeation of drugs through the skin. Although being isotropic …
[HTML][HTML] Nanotechnology: a promising approach for delivery of neuroprotective drugs
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …
major challenge for public health and demand the great attention of researchers to protect …
[HTML][HTML] Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics
YH Choi, HK Han - Journal of pharmaceutical investigation, 2018 - Springer
Nanomedicines have evolved into various forms including dendrimers, nanocrystals,
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …
[HTML][HTML] Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
Strategies to address low drug solubility in discovery and development
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …
therefore, to variability in clinical response. Despite significant efforts to “design in” …
[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …
centuries, modern drug discovery and development pipelines challenge conventional …
50 years of oral lipid-based formulations: provenance, progress and future perspectives
Lipid based formulations (LBF) provide well proven opportunities to enhance the oral
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …
absorption of drugs and drug candidates that sit close to, or beyond, the boundaries of …
Nanodrugs: pharmacokinetics and safety
To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …
In vitro models for the prediction of in vivo performance of oral dosage forms
ES Kostewicz, B Abrahamsson, M Brewster… - European Journal of …, 2014 - Elsevier
Accurate prediction of the in vivo biopharmaceutical performance of oral drug formulations is
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …
Lipid-based formulations for oral administration of poorly water-soluble drugs
Lipid-based drug delivery systems have shown great potentials in oral delivery of poorly
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …