CD38 is a molecule that can act as an enzyme, with NAD-depleting and intracellular
signaling activity, or as a receptor with adhesive functions. CD38 can be found expressed …

Rheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease
associated with decreased life expectancy and quality of life. RA is characterized by chronic …

Meteorin-like, also known as Metrnl, Meteorin-β, Subfatin, and Cometin, is a novel secreted
protein exerting pleiotropic effects on inflammation, immunology, and metabolism. Earlier …

Cytokines are involved in many functions of the immune system including initiating,
amplifying and resolving immune responses. Through bioinformatics analyses of a …

Abstract Heat shock protein 90 (Hsp90) is a molecular chaperone involved in folding and
stabilizing multiple intracellular proteins that have roles in cell activation and proliferation …

So far, there are no means of identifying rheumatoid arthritis (RA) patients who will fail to
respond to tumour necrosis factor blocking agents (anti-TNF), prior to treatment. We set out …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease
characterized by progressive bone and cartilage destruction, functional impairment, and …

In the 1950s, the discovery of autoantibodies produced by B cells seemed to provide a
compelling mechanism underlying autoimmune diseases. The discovery of T regulatory …

Tripterygium glycosides tablets (TGT) are the commonly used preparation for rheumatoid
arthritis (RA). However, the changes in TGT on RA are still unclear at the metabolic level …

Collagen-induced arthritis is the most common in vivo model of rheumatoid arthritis used for
investigation of new potential therapies in preclinical research. Rheumatoid arthritis is a …