Lipid accumulation, inflammation, and oxidative stress are the most important causes of
muscle insulin resistance. The aim of this study was to investigate the single and combined …

Although the exact mechanism linking obesity to type 2 diabetes (T2D) remains unknown,
accumulating evidence suggests that low-grade chronic metabolic inflammation or …

Objectives: The aim of this study was to evaluate the effect of silymarin on liver enzyme
levels and serum lipid profiles in patients with Non-Alcoholic Fatty Liver Disease (NAFLD) …

p-coumaric acid (p-CA), a common plant phenolic acid with multiple bioactivities, has a lipid-
lowering effect. As a dietary polyphenol, its low toxicity, with the advantages of prophylactic …

Obesity, a global health crisis, is associated with metabolic disorders and escalating
healthcare burdens. This review explores the multifaceted dynamics of obesity, investigating …

In individuals with obesity-related non-alcoholic fatty liver disease (NAFLD), endogenous
Glucagon-like peptide-1 (GLP-1) secretion is compromised, and supplementation with GLP …

Emodin has been proven to have weight-reducing and lipid-lowering effects. In order to
make emodin play a better anti-obesity role, we designed and developed an emodin loaded …

Inflammation involving adipose macrophages is an important inducer of obesity. Regulating
macrophages polarization and improving the inflammatory microenvironment of adipose …

Objectives: Increasing evidence has demonstrated that oxidative stress plays a significant
role in the pathogenesis of muscle insulin resistance. The beneficial impacts of genistein …

A large amount of research suggests that polyphenols may have health benefits, particularly
in metabolic disorders associated with obesity, such as non-alcoholic fatty liver (NAFLD) …