Diabetic wound-healing science

JL Burgess, WA Wyant, B Abdo Abujamra, RS Kirsner… - Medicina, 2021 - mdpi.com
Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Skin wound healing process and new emerging technologies for skin wound care and regeneration

EM Tottoli, R Dorati, I Genta, E Chiesa, S Pisani… - Pharmaceutics, 2020 - mdpi.com
Skin wound healing shows an extraordinary cellular function mechanism, unique in nature
and involving the interaction of several cells, growth factors and cytokines. Physiological …

Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Wound dressings functionalized with silver nanoparticles: promises and pitfalls

K Kalantari, E Mostafavi, AM Afifi, Z Izadiyan… - Nanoscale, 2020 - pubs.rsc.org
Infections are the main reason why most people die from burns and diabetic wounds. The
clinical challenge for treating wound infections through traditional antibiotics has been …

Challenges in the treatment of chronic wounds

RG Frykberg, J Banks - Advances in wound care, 2015 - liebertpub.com
Significance: Chronic wounds include, but are not limited, to diabetic foot ulcers, venous leg
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …

[HTML][HTML] Oral wound healing models and emerging regenerative therapies

AI Toma, JM Fuller, NJ Willett, SL Goudy - Translational Research, 2021 - Elsevier
Following injury, the oral mucosa undergoes complex sequences of biological healing
processes to restore homeostasis. While general similarities exist, there are marked …

Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside

D Chouhan, BB Mandal - Acta biomaterialia, 2020 - Elsevier
Silk biomaterials are known for biomedical and tissue engineering applications including
drug delivery and implantable devices owing to their biocompatible and a wide range of …

Recent advancements in biopolymer and metal nanoparticle-based materials in diabetic wound healing management

V Vijayakumar, SK Samal, S Mohanty… - International Journal of …, 2019 - Elsevier
Currently, diabetes mellitus (DM) accelerated diabetic foot ulcer (DFU) remains vivacious
health problem related with delayed healing and high amputation rates which leads to …

Growth factor engineering strategies for regenerative medicine applications

X Ren, M Zhao, B Lash, MM Martino… - … in bioengineering and …, 2020 - frontiersin.org
Growth factors are critical molecules for tissue repair and regeneration. Therefore,
recombinant growth factors have raised a lot of hope for regenerative medicine applications …