The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell …

X Zhang, J Chen, MZ Han, H Huang, E Jiang… - Journal of hematology & …, 2021 - Springer
The consensus recommendations in 2018 from The Chinese Society of Hematology (CSH)
on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem …

KIR receptors as key regulators of NK cells activity in health and disease

J Dębska-Zielkowska, G Moszkowska, M Zieliński… - Cells, 2021 - mdpi.com
Natural killer (NK) cells are part of the cellular immune response. They target mainly cancer
and virally infected cells. To a high extent cytotoxic activity of NK cells is regulated inter alia …

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

H Döhner, AH Wei, FR Appelbaum… - Blood, The Journal …, 2022 - ashpublications.org
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …

National Marrow Donor Program–sponsored multicenter, phase II trial of HLA-mismatched unrelated donor bone marrow transplantation using post-transplant …

BE Shaw, AM Jimenez-Jimenez, LJ Burns… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Hematopoietic cell transplantation (HCT) is curative for hematologic disorders,
but outcomes are historically inferior when using HLA-mismatched donors. Despite …

Umbilical cord blood transplantation: Still growing and improving

X Zhu, B Tang, Z Sun - Stem cells translational medicine, 2021 - academic.oup.com
Umbilical cord blood transplantation (UCBT) has been performed in the clinic for over 30
years. The biological and immunological characteristics of umbilical cord blood (UCB) have …

Post-transplant cyclophosphamide–based graft-versus-host disease prophylaxis attenuates disparity in outcomes between use of matched or mismatched unrelated …

BC Shaffer, M Gooptu, TE DeFor, M Maiers… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Access to allogeneic hematopoietic cell transplantation (HCT) remains limited
among persons of non-European ancestry if human leukocyte antigen (HLA) matching is …

Clonal hematopoiesis and its emerging effects on cellular therapies

M von Bonin, HK Jambor, R Teipel, F Stölzel, C Thiede… - Leukemia, 2021 - nature.com
The accumulation of somatic mutations in hematopoietic stem cells during aging, leading to
clonal expansion, is linked to a higher risk of cardiovascular mortality and hematologic …

Younger unrelated donors may be preferable over HLA match in the PTCy era: a study from the ALWP of the EBMT

J Sanz, M Labopin, G Choi, A Kulagin, J Peccatori… - Blood, 2024 - ashpublications.org
There is a paucity of information on how to select the most appropriate unrelated donor (UD)
in hematopoietic stem cell transplantation (HSCT) using posttransplant cyclophosphamide …

Are haematopoietic stem cell transplants stem cell transplants, is there a threshold dose of CD34-positive cells and how many are needed for rapid posttransplant …

J Chen, RP Gale, Y Feng, Y Hu, S Qi, X Liu, H Zhu… - Leukemia, 2023 - nature.com
It is widely-believed recovery of bone marrow function after a haematopoietic cell transplant
arises from pluripotent haematopoietic stem cells (HSCs; hence haematopoietic stem cell …

[HTML][HTML] Guidelines for cord blood unit selection

I Politikos, E Davis, M Nhaissi, JE Wagner… - Biology of Blood and …, 2020 - Elsevier
Optimal cord blood (CB) unit selection is critical to maximize the likelihood of successful
engraftment and survival after CB transplantation (CBT). However, unit selection can be …