Cardiac fibrosis is a common pathophysiologic companion of most myocardial diseases,
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …

As a result of over five decades of investigation, mesenchymal stromal/stem cells (MSCs)
have emerged as a versatile and frequently utilized cell source in the fields of regenerative …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a broad range
of clinical responses including prominent microvascular damage. The capacity of SARS …

Brain vascular calcification is a prevalent age-related condition often accompanying
neurodegenerative and neuroinflammatory diseases. The pathogenesis of large-vessel …

Pericytes are widely believed to function as mesenchymal stem cells (MSCs), multipotent
tissue-resident progenitors with great potential for regenerative medicine. Cultured pericytes …

Pericytes, attached to the surface of capillaries, play an important role in regulating local
blood flow. Using optogenetic tools and genetically encoded reporters in conjunction with …

Pericytes are mural cells surrounding blood vessels, adjacent to endothelial cells. Pericytes
play critical roles in maturation and maintenance of vascular branching morphogenesis. In …

Mural cells of the vessel wall, namely pericytes and vascular smooth muscle cells, are
essential for vascular integrity. The developmental sources of these cells and molecular …

Epicardial cells on the heart's surface give rise to coronary artery smooth muscle cells
(caSMCs) located deep in the myocardium. However, the differentiation steps between …

The vasculature plays an indispensible role in organ development and maintenance of
tissue homeostasis, such that disturbances to it impact greatly on developmental and …