Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
Recent advances in the synthesis of biologically active spirooxindoles
MMM Santos - Tetrahedron, 2014 - Elsevier
The spirooxindole system is the core structure of a variety of medicinal agents and natural
products. 1, 2 In fact, spirooxindole derivatives have been described with different biological …
products. 1, 2 In fact, spirooxindole derivatives have been described with different biological …
Natural compounds as medical strategies in the prevention and treatment of psychiatric disorders seen in neurological diseases
E Küpeli Akkol, I Tatlı Çankaya… - Frontiers in …, 2021 - frontiersin.org
Psychiatric disorders are frequently encountered in many neurological disorders, such as
Alzheimer's and Parkinson diseases along with epilepsy, migraine, essential tremors, and …
Alzheimer's and Parkinson diseases along with epilepsy, migraine, essential tremors, and …
Plant alkaloids as drug leads for Alzheimer's disease
YP Ng, TCT Or, NY Ip - Neurochemistry international, 2015 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative illness associated with dementia and is
most prevalent among the elderly population. Current medications can only treat symptoms …
most prevalent among the elderly population. Current medications can only treat symptoms …
[HTML][HTML] Role of plant derived alkaloids and their mechanism in neurodegenerative disorders
Neurodegenerative diseases are conventionally demarcated as disorders with selective loss
of neurons. Conventional as well as newer molecules have been tested but they offer just …
of neurons. Conventional as well as newer molecules have been tested but they offer just …
Medicinal uses, phytochemistry and pharmacology of the genus Uncaria
Q Zhang, JJ Zhao, J Xu, F Feng, W Qu - Journal of Ethnopharmacology, 2015 - Elsevier
Abstract Ethnopharmacological relevance The genus Uncaria belongs to the family
Rubiaceae, which mainly distributed in tropical regions, such as Southeast Asia, Africa and …
Rubiaceae, which mainly distributed in tropical regions, such as Southeast Asia, Africa and …
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry
N Qin, X Lu, Y Liu, Y Qiao, W Qu, F Feng… - European Journal of …, 2021 - Elsevier
Medicinal plants are well-known in affording clinically useful agents, with rich medicinal
values by combining with disease targets through various mechanisms. Plant secondary …
values by combining with disease targets through various mechanisms. Plant secondary …
Attenuation of Nrf2/Keap1/ARE in Alzheimer's disease by plant secondary metabolites: A mechanistic review
Alzheimer's disease (AD) is a progressive neuronal/cognitional dysfunction, leading to
disability and death. Despite advances in revealing the pathophysiological mechanisms …
disability and death. Despite advances in revealing the pathophysiological mechanisms …
Phellodendri cortex: a phytochemical, pharmacological, and pharmacokinetic review
Background. Phellodendri Cortex (PC) or Huang Bai. According to the scientific database of
China Plant Species and Chinese pharmacopeia 2015 edition, PC has two main species …
China Plant Species and Chinese pharmacopeia 2015 edition, PC has two main species …
Traditional Ayurvedic and herbal remedies for Alzheimer's disease: from bench to bedside
Introduction: Alzheimer's disease (AD) is a progressive, neurodegenerative disorder
prevalent worldwide among elderly populations. Owing to limited efficacy, side effects, and …
prevalent worldwide among elderly populations. Owing to limited efficacy, side effects, and …