Brain dopamine (DA) has long been implicated in cognitive control processes, including
working memory. However, the precise role of DA in cognition is not well-understood, partly …

Executive dysfunction can be present from the early stages of P arkinson's disease (PD). It is
characterized by deficits in internal control of attention, set shifting, planning, inhibitory …

Abstract 'Brain training', or the goal of improved cognitive function through the regular use of
computerized tests, is a multimillion-pound industry, yet in our view scientific evidence to …

Research into the heterogeneous nature of cognitive impairment documented in patients
with Parkinson's disease (PD) has focused on disentangling deficits that vary between …

Cognitive impairment in patients with Parkinson's disease is gaining increased clinical
significance owing to the relative success of therapeutic approaches to the motor symptoms …

The recent formalization of clinical criteria for Parkinson's disease with dementia (PDD)
codifies many studies on this topic, including those assessing biological correlates. These …

A dopaminergic deficiency in patients with Parkinson's disease (PD) causes abnormalities of
movement, behaviour, learning, and emotions. The main motor features (ie, tremor, rigidity …

Cognitive abnormalities are common in Parkinson's disease, with important social and
economic implications. Factors influencing their evolution remain unclear but are crucial to …

Motor development and cognitive development may be fundamentally interrelated. Contrary
to popular notions that motor development begins and ends early, whereas cognitive …

The traditional view that the basal ganglia and cerebellum are simply involved in the control
of movement has been challenged in recent years. One of the pivotal reasons for this …