Interplay of calcium and cadmium in mediating cadmium toxicity

G Choong, Y Liu, DM Templeton - Chemico-biological interactions, 2014 - Elsevier
The environmentally important toxic metal, cadmium, exists as the Cd 2+ ion in biological
systems, and in this state structurally resembles Ca 2+. Thus, although cadmium exerts a …

Melatonin signaling and cell protection function

F Luchetti, B Canonico, M Betti… - The FASEB …, 2010 - Wiley Online Library
Besides its well‐known regulatory role on circadian rhythm, the pineal gland hormone
melatonin has other biological functions and a distinct metabolism in various cell types and …

Current Understanding of Pneumocystis Immunology

MN Kelly, JE Shellito - Future microbiology, 2010 - Taylor & Francis
Pneumocystis jirovecii is the opportunistic fungal organism that causes Pneumocystis
pneumonia (PCP) in humans. Similar to other opportunistic pathogens, Pneumocystis …

Differential macrophage polarization from pneumocystis in immunocompetent and immunosuppressed hosts: potential adjunctive therapy during pneumonia

V Nandakumar, D Hebrink, P Jenson… - Infection and …, 2017 - Am Soc Microbiol
We explored differential polarization of macrophages during infection using a rat model of
Pneumocystis pneumonia. We observed enhanced pulmonary M1 macrophage polarization …

Role of Calmodulin-Calmodulin Kinase II, cAMP/Protein Kinase A and ERK 1/2 on Aeromonas hydrophila-Induced Apoptosis of Head Kidney Macrophages

C Banerjee, P Khatri, R Raman, H Bhatia… - PLoS …, 2014 - journals.plos.org
The role of calcium (Ca2+) and its dependent protease calpain in Aeromonas hydrophila-
induced head kidney macrophage (HKM) apoptosis has been reported. Here, we report the …

Defective Nitric Oxide Production by Alveolar Macrophages during Pneumocystis Pneumonia

ME Lasbury, CP Liao, CA Hage, PJ Durant… - American journal of …, 2011 - atsjournals.org
The effect of nitric oxide (NO) on Pneumocystis (Pc) organisms, the role of NO in the defense
against infection with Pc, and the production of NO by alveolar macrophages (AMs) during …

The Protein Backbone Phi and Psi Angles Define a Universal Feature Set for Machine Learning Prediction of the Phenotypic Effects of Genetic Variants

JR Hamre III - 2021 - search.proquest.com
Mutagenic pathogenesis and acquired drug resistance are leading obstacles in disease
management and current therapies. Molecular dynamics simulations are now technically …

[图书][B] HOX/PBX interaction as a therapeutic target in Acute Myeloid Leukaemia

R Alharbi - 2015 - search.proquest.com
Acute myeloid leukaemia (AML) is a disorder characterised by the accumulation of blast
cells or progenitors of one of several non-lymphoid haematopoietic cell lineages and is …

The integration of large biological and clinical datasets towards the understanding of human disease

SW Robinson - 2020 - theses.gla.ac.uk
As the cost of high-throughput techniques reduces, and new more powerful equipment is
designed, more highly-dimensional biological data will be available–and a lot of data is …

[PDF][PDF] Role of Calmodulin-Calmodulin Kinase II, cAMP

C Banerjee, P Khatri, R Raman, H Bhatia… - Protein Kinase A and …, 2014 - academia.edu
The role of calcium (Ca2+) and its dependent protease calpain in Aeromonas hydrophila-
induced head kidney macrophage (HKM) apoptosis has been reported. Here, we report the …