Most of oral targeted therapies are tyrosine kinase inhibitors (TKIs). Oral administration
generates a complex step in the pharmacokinetics (PK) of these drugs. Inter-individual PK …

Metabolism represents the most prevalent mechanism for drug clearance. Many drugs are
converted to metabolites that can retain the intrinsic affinity of the parent drug for the …

Interaction of pharmacologically important anticancer drug cytosine β-D arabinofuranoside
with human serum albumin (HSA) at physiological pH 7.4 has been studied by utilizing …

The interactions between estradiol and two carrier proteins, ie human serum albumin (HSA)
and holo-transferrin (HTF) in aqueous solution at pH= 7.4 were studied by three …

The interaction between metformin and human serum albumin (HSA), as well as its glycated
form (gHSA) was investigated by multiple spectroscopic techniques, zeta potential, and …

Human serum albumin (HSA) is one of the most widely studied proteins and is an important
plasma protein responsible for binding and transport of many exogenous and endogenous …

The interaction of amodiaquine (AQ) with human serum albumin (HSA) has been studied by
fluorescence spectroscopy. Based on the sign and magnitude of the enthalpy and entropy …

We have studied the binding of busulfan (BN) to human serum albumin (HSA) at
physiological pH 7.4 by using fluorescence, UV–vis and circular dichroism (CD) …

Human serum albumin (HSA) is the major plasma protein with vital functions acting as depot
and career for many endogenous (fatty acids, bilirubin, etc.) and exogenous substances …

Chemometrics is chemical discipline in which mathematical and statistical methods are
coupled with chemical data to extract useful information which cannot be extracted by the …