Imaging biomarkers for the diagnosis and prognosis of neurodegenerative diseases. The example of amyotrophic lateral sclerosis

M Mazón, JF Vázquez Costa, A Ten-Esteve… - Frontiers in …, 2018 - frontiersin.org
The term amyotrophic lateral sclerosis (ALS) comprises a heterogeneous group of fatal
neurodegenerative disorders of largely unknown etiology characterized by the upper motor …

Feature selection from magnetic resonance imaging data in ALS: a systematic review

TD Kocar, HP Mueller, AC Ludolph… - … advances in chronic …, 2021 - journals.sagepub.com
Background: With the advances in neuroimaging in amyotrophic lateral sclerosis (ALS), it
has been speculated that multiparametric magnetic resonance imaging (MRI) is capable to …

Quantitative susceptibility mapping of the motor cortex: a comparison of susceptibility among patients with amyotrophic lateral sclerosis, cerebrovascular disease, and …

JY Lee, YJ Lee, DW Park, Y Nam, SH Kim, J Park… - Neuroradiology, 2017 - Springer
Purpose The purpose of this study was to investigate the differences in motor cortex
susceptibility among patients with amyotrophic lateral sclerosis (ALS), cerebrovascular …

White matter volume loss in amyotrophic lateral sclerosis: a meta-analysis of voxel-based morphometry studies

G Chen, B Zhou, H Zhu, W Kuang, F Bi, H Ai… - Progress in Neuro …, 2018 - Elsevier
Structural neuroimaging studies of white matter (WM) volume in amyotrophic lateral
sclerosis (ALS) using voxel-based morphometry (VBM) have yielded inconsistent findings …

Motor cortex hypointensity on susceptibility-weighted imaging: a potential imaging marker of iron accumulation in patients with cognitive impairment

M Park, Y Moon, SH Han, WJ Moon - Neuroradiology, 2019 - Springer
Purpose To assess the prevalence and characteristics of motor cortex hypointensity on 3-T
susceptibility-weighted imaging (SWI) in patients with cognitive impairment and examine its …

MR findings in the substantia nigra on phase difference enhanced imaging in neurodegenerative parkinsonism

A Sugiyama, N Sato, Y Kimura, M Ota… - Parkinsonism & Related …, 2018 - Elsevier
Abstract Introduction In Parkinson's disease (PD) patients, magnetic resonance (MR)
imaging studies using phase difference enhanced imaging (PADRE) and susceptibility …

Low signal intensity in motor cortex on susceptibility-weighted MR imaging is correlated with clinical signs of amyotrophic lateral sclerosis: a pilot study

H Endo, K Sekiguchi, H Shimada, T Ueda, H Kowa… - Journal of …, 2018 - Springer
There is no reliable objective indicator for upper motor neuron dysfunction in amyotrophic
lateral sclerosis (ALS). To determine the clinical significance and potential utility of magnetic …

Potential usefulness of signal intensity of cerebral gyri on quantitative susceptibility mapping for discriminating corticobasal degeneration from progressive …

M Miyata, S Kakeda, Y Toyoshima, S Ide, K Okada… - Neuroradiology, 2019 - Springer
Purpose The typical MRI findings in corticobasal degeneration (CBD), which have been
described in previous reports, may be non-specific. We evaluated cerebral gyri (CG) using …

Differentiation of brain metastases and gliomas based on color map of phase difference enhanced imaging

S Doishita, S Sakamoto, T Yoneda, T Uda… - Frontiers in …, 2018 - frontiersin.org
Background and objective: Phase difference enhanced imaging (PADRE), a new phase-
related MRI technique, can enhance both paramagnetic and diamagnetic substances, and …

Facial nerve atrophy in patients with amyotrophic lateral sclerosis: evaluation with fast imaging employing steady‐state acquisition (FIESTA)

M Miyata, S Kakeda, T Hashimoto, S Ide… - Journal of Magnetic …, 2020 - Wiley Online Library
Background In amyotrophic lateral sclerosis (ALS), motor neurons in the brainstem markedly
deplete, whereas sensory neurons are less severely affected. Purpose To determine …