Biological phase separation: cell biology meets biophysics

T Yoshizawa, RS Nozawa, TZ Jia, T Saio, E Mori - Biophysical reviews, 2020 - Springer
Progress in development of biophysical analytic approaches has recently crossed paths with
macromolecule condensates in cells. These cell condensates, typically termed liquid-like …

Blastic plasmacytoid dendritic cell neoplasm: state of the art and prospects

MR Sapienza, A Pileri, E Derenzini, F Melle, G Motta… - Cancers, 2019 - mdpi.com
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare tumour, which
usually affects elderly males and presents in the skin with frequent involvement of the bone …

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

F Garnache-Ottou, C Vidal, S Biichlé, F Renosi… - Blood …, 2019 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive leukemia for
which we developed a nationwide network to collect data from new cases diagnosed in …

Multicenter analysis of outcomes in blastic plasmacytoid dendritic cell neoplasm offers a pretargeted therapy benchmark

J Taylor, M Haddadin, VA Upadhyay… - Blood, The Journal …, 2019 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an uncommon hematologic
malignancy with poor outcomes. Existing data on the clinical behavior of BPDCN are limited …

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need

N Pemmaraju, H Kantarjian, K Sweet, E Wang… - Blood, 2023 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
with historically poor outcomes and no worldwide consensus treatment approach. Unique …

Abiotic microcompartments form when neighbouring droplets fuse: an electrochemiluminescence investigation

S Voci, TB Clarke, JE Dick - Chemical Science, 2023 - pubs.rsc.org
Many studies have shown chemistry proceeds differently in small volumes compared to bulk
phases. However, few studies exist elucidating spontaneous means by which small volumes …

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

F Renosi, A Roggy, A Giguelay, L Soret… - Blood …, 2021 - ashpublications.org
Oncogenesis and ontogeny of blastic plasmacytoid dendritic cell neoplasm (BPDCN) remain
uncertain, between canonical plasmacytoid dendritic cells (pDCs) and AXL+ SIGLEC6+ DCs …

Nuclear microenvironment in cancer: Control through liquid‐liquid phase separation

RS Nozawa, T Yamamoto, M Takahashi… - Cancer …, 2020 - Wiley Online Library
The eukaryotic nucleus is not a homogenous single‐spaced but a highly compartmentalized
organelle, partitioned by various types of membraneless structures, including nucleoli, PML …

Novel therapeutic approaches in blastic plasmacytoid dendritic cell neoplasm (BPDCN): era of targeted therapy

NR Wilson, M Konopleva, JD Khoury… - … Lymphoma Myeloma and …, 2021 - Elsevier
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
arising from the aberrant transformation of plasmacytoid dendritic cells (pDCs) and involving …

Blastic plasmacytoid dendritic cell neoplasm–current insights

S Venugopal, S Zhou, SM El Jamal, AA Lane… - … Myeloma and Leukemia, 2019 - Elsevier
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare clonal hematologic
malignancy of plasmacytoid dendritic cell precursors. The presentation and clinical course of …