Cancer has long been viewed as a disease of normal development gone awry. Cancer stem-
like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as …

Cancer stem cells (CSCs) represent a tumor subpopulation responsible for tumor metastasis
and resistance to chemo-and radiotherapy, ultimately leading to tumor relapse. As a …

Although breast cancer stem cells (BCSCs) display plasticity transitioning between
quiescent mesenchymal-like (M) and proliferative epithelial-like (E) states, how this plasticity …

The existence of breast cancer stem cells (BCSCs) is a major reason underlying cancer
metastasis and recurrence after chemotherapy and radiotherapy. Targeting BCSCs may …

Background Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast
cancer with poor prognosis and limited treatment. As a major component of the tumor …

Aberrant expression of XIST, a long noncoding RNA (lncRNA) initiating X chromosome
inactivation (XCI) in early embryogenesis, is a common feature of breast cancer (BC) …

Background and objectives: Cancer stem cells (CSCs) have been implicated in tumor
initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast …

With the highest incidence, breast cancer is the leading cause of cancer deaths among
women in the world. Tumor metastasis is the major contributor of high mortality in breast …

Circulating tumor cells (CTCs) have become an established biomarker for prognosis in
patients with various carcinomas. However, current ex vivo CTC isolation technologies rely …

Triple-negative breast cancer (TNBC) remains a clinical challenge because of the absence
of effective therapeutic targets. In TNBC, overexpression of YAP and TAZ correlates with …