Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Bacteria in cancer initiation, promotion and progression

G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

[HTML][HTML] Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Microbiota-mediated colonization resistance: mechanisms and regulation

G Caballero-Flores, JM Pickard, G Núñez - Nature Reviews …, 2023 - nature.com
A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

[HTML][HTML] Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases

MR Mahmud, S Akter, SK Tamanna, L Mazumder… - Gut …, 2022 - Taylor & Francis
The human intestine hosts diverse microbial communities that play a significant role in
maintaining gut-skin homeostasis. When the relationship between gut microbiome and the …

Staphylococcus epidermidis and its dual lifestyle in skin health and infection

MM Severn, AR Horswill - Nature Reviews Microbiology, 2023 - nature.com
The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

[HTML][HTML] Skin barrier function and the microbiome

HJ Lee, M Kim - International journal of molecular sciences, 2022 - mdpi.com
Human skin is the largest organ and serves as the first line of defense against environmental
factors. The human microbiota is defined as the total microbial community that coexists in the …

Current understanding of the human microbiome

JA Gilbert, MJ Blaser, JG Caporaso, JK Jansson… - Nature medicine, 2018 - nature.com
Our understanding of the link between the human microbiome and disease, including
obesity, inflammatory bowel disease, arthritis and autism, is rapidly expanding …

[HTML][HTML] Challenges in exploring and manipulating the human skin microbiome

M Boxberger, V Cenizo, N Cassir, B La Scola - Microbiome, 2021 - Springer
The skin is the exterior interface of the human body with the environment. Despite its harsh
physical landscape, the skin is colonized by diverse commensal microbes. In this review, we …