Metal-tolerant thermophiles: metals as electron donors and acceptors, toxicity, tolerance and industrial applications

P Ranawat, S Rawat - Environmental Science and Pollution Research, 2018 - Springer
Metal-tolerant thermophiles are inhabitants of a wide range of extreme habitats like solfatara
fields, hot springs, mud holes, hydrothermal vents oozing out from metal-rich ores …

Comparative genomic analysis of the DUF34 protein family suggests role as a metal ion chaperone or insertase

CJ Reed, G Hutinet, V de Crécy-Lagard - Biomolecules, 2021 - mdpi.com
Members of the DUF34 (domain of unknown function 34) family, also known as the NIF3
protein superfamily, are ubiquitous across superkingdoms. Proteins of this family have been …

[HTML][HTML] Ultrastructural and morphometrical changes of mice ovaries following experimentally induced copper poisoning

H Babaei, L Roshangar, E Sakhaee… - Iranian Red Crescent …, 2012 - ncbi.nlm.nih.gov
Background Copper (Cu) is an essential trace element involved in normal reproduction but
its overexposure may produce some detrimental effects. The aim of this study was to …

In Vitro Cytotoxic Effect of Aqueous Extracts from Leaves and Rhizomes of the Seagrass Posidonia oceanica (L.) Delile on HepG2 Liver Cancer Cells: Focus on …

G Abruscato, R Chiarelli, V Lazzara, D Punginelli… - Biology, 2023 - mdpi.com
Simple Summary Posidonia oceanica is a widely distributed and abundant endemic
seagrass in the Mediterranean area. In the attempt to identify new compounds that might …

The effects of copper toxicity on histopathological and morphometrical changes of the rat testes

H Babaei, R Kheirandish, L Ebrahimi - Asian Pacific Journal of Tropical …, 2012 - Elsevier
Objective Exposure to environmental toxicants such as copper has been suggested to have
adverse effects on male reproduction. Therefore, our aim in the present study was to …

The role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation

P Hou, G Liu, Y Zhao, Z Shi, Q Zheng, G Bu, H Xu… - Neurobiology of …, 2015 - Elsevier
One major pathologic hallmark and trigger of Alzheimer's disease (AD) is overproduction
and accumulation of β-amyloid (Aβ) species in the brain. Aβ is derived from β-amyloid …

Effects of copper ions released from metallic copper on CHO-K1 cells

CA Grillo, MA Reigosa, MFL de Mele - Mutation Research/Genetic …, 2009 - Elsevier
The aim of this study was to investigate the cytotoxic and genotoxic effect of copper extracts
obtained from metallic copper in Chinese hamster ovary (CHO-K1) cell line using neutral red …

CutA divalent cation tolerance homolog (Escherichia coli)(CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP …

Y Zhao, Y Wang, J Hu, X Zhang, Y Zhang - Journal of Biological Chemistry, 2012 - ASBMB
Accumulation of the neurotoxic β-amyloid (Aβ) peptide in the brain is central to the
pathogenesis of Alzheimer disease. Aβ is derived from the β-amyloid precursor protein …

Survival of the fittest: overcoming oxidative stress at the extremes of acid, heat and metal

Y Maezato, P Blum - Life, 2012 - mdpi.com
The habitat of metal respiring acidothermophilic lithoautotrophs is perhaps the most
oxidizing environment yet identified. Geothermal heat, sulfuric acid and transition metals …

Protein CutA undergoes an unusual transfer into the secretory pathway and affects the folding, oligomerization, and secretion of acetylcholinesterase

D Liang, N Nunes-Tavares, HQ Xie, S Carvalho… - Journal of biological …, 2009 - ASBMB
The mammalian protein CutA was first discovered in a search for the membrane anchor of
mammalian brain acetylcholinesterase (AChE). It was co-purified with AChE, but it is distinct …