PERSIST: a programmable RNA regulation platform using CRISPR endoRNases

B DiAndreth, N Wauford, E Hu, S Palacios, R Weiss - BioRxiv, 2019 - biorxiv.org
Regulation of transgene expression is becoming an integral component of gene therapies,
cell therapies and biomanufacturing. However, transcription factor-based regulation upon …

[HTML][HTML] Freeing genetic circuits from the messy cellular context

D Del Vecchio - communities.springernature.com
Freeing genetic circuits from the messy cellular context | Research Communities by
Springer Nature Share your thoughts about the Research Communities in our survey …

On the Deviant Behavior of Synthetic Gene Networks in Genomic and Transient Context or: How I Stopped Worrying about Stable Cell Lines and Started Loving …

C Stelzer - 2020 - research-collection.ethz.ch
The mapping of inputs to their molecular outputs is of pivotal interest in biolog-ical research.
In the field of synthetic biology, this became a standard analysis technique to characterize …

Design trade-offs and robust architectures for combined transcriptional and translational resource allocation controllers

APS Darlington, DG Bates - bioRxiv, 2020 - biorxiv.org
Recent work on engineering synthetic cellular circuitry has shown that non-regulatory
interactions brought about through competition for shared gene expression resources, such …