Peptides and peptide hormones for molecular imaging and disease diagnosis

S Lee, J Xie, X Chen - Chemical reviews, 2010 - ACS Publications
Molecular imaging techniques are now indispensable tools in modern diagnostics, because
they are highly specific and can provide biological information at the molecular level in living …

Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions

P Jayachandran, F Battaglin, C Strelez, A Lenz… - Oncogene, 2023 - nature.com
Exploring the relationship between various neurotransmitters and breast cancer cell growth
has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters …

A Markov random field model for network-based analysis of genomic data

Z Wei, H Li - Bioinformatics, 2007 - academic.oup.com
Motivation: A central problem in genomic research is the identification of genes and
pathways involved in diseases and other biological processes. The genes identified or the …

Target-specific delivery of peptide-based probes for PET imaging

K Chen, PS Conti - Advanced drug delivery reviews, 2010 - Elsevier
Positron emission tomography (PET) is one of the most rapidly growing areas of medical
imaging, with many applications in the clinical management of patients with various …

Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells

J Li, E Li, RS Czepielewski, J Chi, X Guo, YH Han… - Cell metabolism, 2021 - cell.com
The lymphatic vasculature plays important roles in the physiology of the organs in which it
resides, though a clear mechanistic understanding of how this crosstalk is mediated is …

Plasma proneurotensin and incidence of diabetes, cardiovascular disease, breast cancer, and mortality

O Melander, AS Maisel, P Almgren, J Manjer, M Belting… - Jama, 2012 - jamanetwork.com
Context Neurotensin regulates both satiety and breast cancer growth in the experimental
setting, but little is known about its role in the development of breast cancer or …

[HTML][HTML] The molecular mechanism of chronic stress affecting the occurrence and development of breast cancer and potential drug therapy

H Liu, C Li, B Cao, Y Jiang, L Han, R Xu, J Lin… - Translational …, 2022 - Elsevier
According to the 2020 data released by the International Agency for Research on Cancer,
breast cancer has surpassed lung cancer as the world's most newly diagnosed first-time …

Radiometallated peptides for molecular imaging and targeted therapy

JDG Correia, A Paulo, PD Raposinho, I Santos - Dalton Transactions, 2011 - pubs.rsc.org
In developed countries, cancer is the second leading cause of death, being only surpassed
by cardiovascular diseases. To develop tumor-targeted tools to localize and treat cancer at …

Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy

Z Wu, D Martinez-Fong, J Trédaniel… - Frontiers in …, 2013 - frontiersin.org
Cancer is a worldwide health problem. Personalized treatment represents a future
advancement for cancer treatment, in part due to the development of targeted therapeutic …

1, 4-Disubstituted 1, 2, 3-triazoles as amide bond surrogates for the stabilisation of linear peptides with biological activity

LM Rečnik, W Kandioller, TL Mindt - Molecules, 2020 - mdpi.com
Peptides represent an important class of biologically active molecules with high potential for
the development of diagnostic and therapeutic agents due to their structural diversity …