[HTML][HTML] Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty
C Badowski, B He, LX Garmire - NPJ precision oncology, 2022 - nature.com
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
Omics approaches for the assessment of biological responses to nanoparticles
Y Abdelkader, L Perez-Davalos, R LeDuc… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology has enabled the development of innovative therapeutics, diagnostics, and
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …
[HTML][HTML] TPM, FPKM, or normalized counts? A comparative study of quantification measures for the analysis of RNA-seq data from the NCI patient-derived models …
Background In order to correctly decode phenotypic information from RNA-sequencing
(RNA-seq) data, careful selection of the RNA-seq quantification measure is critical for inter …
(RNA-seq) data, careful selection of the RNA-seq quantification measure is critical for inter …
A cascade nanozyme with amplified sonodynamic therapeutic effects through comodulation of hypoxia and immunosuppression against cancer
The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal
to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell …
to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell …
Sampling the proteome by emerging single-molecule and mass spectrometry methods
MJ MacCoss, JA Alfaro, DA Faivre, CC Wu… - nature methods, 2023 - nature.com
Mammalian cells have about 30,000 times as many protein molecules as mRNA molecules,
which has major implications in the development of proteomics technologies. We discuss …
which has major implications in the development of proteomics technologies. We discuss …
[HTML][HTML] Gene expression based inference of cancer drug sensitivity
S Chawla, A Rockstroh, M Lehman, E Ratther… - Nature …, 2022 - nature.com
Inter and intra-tumoral heterogeneity are major stumbling blocks in the treatment of cancer
and are responsible for imparting differential drug responses in cancer patients. Recently …
and are responsible for imparting differential drug responses in cancer patients. Recently …
[HTML][HTML] Growth promotion and antibiotic induced metabolic shifts in the chicken gut microbiome
Antimicrobial growth promoters (AGP) have played a decisive role in animal agriculture for
over half a century. Despite mounting concerns about antimicrobial resistance and demand …
over half a century. Despite mounting concerns about antimicrobial resistance and demand …
[HTML][HTML] Identification and characterization of a novel molecular classification based on disulfidptosis-related genes to predict prognosis and immunotherapy efficacy in …
L Yang, W Zhang, Y Yan - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Disulfidptosis has been discovered as a mechanism of cell death mediating by
SLC7A11. Nonetheless, little is known about the relationship between disulfidptosis-related …
SLC7A11. Nonetheless, little is known about the relationship between disulfidptosis-related …
[HTML][HTML] Identification and validation of immunotherapy for four novel clusters of colorectal cancer based on the tumor microenvironment
The incidence and mortality of colorectal cancer (CRC) are increasing year by year. The
accurate classification of CRC can realize the purpose of personalized and precise …
accurate classification of CRC can realize the purpose of personalized and precise …
[HTML][HTML] Roles of m5C RNA modification patterns in biochemical recurrence and tumor microenvironment characterization of prostate adenocarcinoma
Z Xu, S Chen, Y Zhang, R Liu, M Chen - Frontiers in Immunology, 2022 - frontiersin.org
Background Prostate cancer is the second most common cancer with a high risk of
biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification …
biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification …