Oxytocin (OXT) and arginine-vasopressin (AVP) are structurally homologous peptide
hormones synthesized in the hypothalamus. Nowadays, the role of OXT and AVP in the …

Mental disorders such as anxiety and depression induced by chronic pain are common in
clinical practice, and there are significant sex differences in their epidemiology. However …

Background Due to its potent effects on social behavior, including maternal behavior,
oxytocin has been identified as a potential mediator of postpartum depression and anxiety …

Risk and resilience in brain health and disease can be influenced by a variety of factors.
While there is a growing appreciation to consider sex as one of these factors, far less …

Anxiety and mood disorders are prevalent, disabling, and frequently difficult to treat. Such
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …

Objective: Oxytocin (OT) synchrony has been suggested as a key mechanism by which
bonds are formed and strengthened in various species, including those between mother and …

The experience of motherhood is most often emotionally positive and rewarding, but for
many new mothers suffering from postpartum depression (PPD), this is not the case …

Novel pharmacotherapies that improve outcomes for individuals with stress-related
psychiatric disorders are needed. The neurohormone oxytocin (OT) is a promising candidate …

The oxytocin system is involved in psychological functions and interacts with biological
systems that are altered in patients suffering from depressive disorders. This suggests a …

Abstract About 20–30% of patients with major depressive disorder (MDD) develop treatment-
resistant depression (TRD) and finding new effective treatments for TRD has been a …