Mesenchymal stem cells (MSCs), due to their paracrine, transdifferentiation, and
immunosuppressive effects, hold great promise as a therapy for peripheral arterial disease …

Critical limb ischemia (CLI) is a syndrome manifested by ischemic rest pain, non-healing
ulcers and tissue loss. CLI patients are at very high risk of amputation and experience poor …

The mucosal immune network is a crucial barrier preventing pathogens from entering the
body. The network of immune cells that mediates the defensive mechanisms in the mucosa …

Recently, we identified extracellular ubiquitin as an endogenous CXC chemokine receptor
(CXCR) 4 agonist. However, the receptor selectivity and molecular basis of the CXCR4 …

Objective The aim was to identify the change in gene expression between mesenchymal
stem cells (MSCs) and induced endothelial cells (ECs) and to investigate the potential …

Background: Cell therapy is a therapeutic option for patients presenting with
nonrevascularizable critical limb ischemia (CLI). However there is a lack of firm evidence on …

Introduction Treatment of chronic skin wounds is difficult and largely ineffective. Little
improvement has been shown in promoting the healing of these wounds in the past few …

Ubiquitin, a post-translational protein modifier inside the cell, functions as a CXC chemokine
receptor (CXCR) 4 agonist outside the cell. However, the structural determinants of the …

Psoriasis is a complex chronic relapsing inflammatory disease. Although the exact
mechanism remains unknown, it is commonly accepted that the development of psoriasis is …

Abstract Development of thoracolumbar vertebra (TLV) and rib primordium (RP) is a
common evolutionary feature across vertebrates, although whole-organism analysis of the …