The aim of this ESC Guideline is to help health professionals manage people with heart
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …

Frailty, a consequence of the interaction of the aging process and certain chronic diseases,
compromises functional outcomes in the elderly and substantially increases their risk for …

Abstract Document Reviewers: Rudolf A. de Boer (CPG Review Coordinator)(Netherlands),
P. Christian Schulze (CPG Review Coordinator)(Germany), Magdy Abdelhamid (Egypt) …

Cochrane, Maria Crespo Leiro, Anne Dipchand, Brian Feingold, Kathleen Grady, Edward
Horn, Maryl Johnson, Donna Mancini, Sean Pinney, Heather Ross, Kari Wujcik, Andreas …

Background: Frailty may modify the risk− benefit profile of certain treatments, and frail
patients may have reduced tolerance to treatments. Objective: To investigate the efficacy of …

Background: Frailty is increasing in prevalence. Because patients with frailty are often
perceived to have a less favorable risk/benefit profile, they may be less likely to receive new …

Abstract Background The Short Physical Performance Battery (SPPB) is a well-established
tool to assess lower extremity physical performance status. Its predictive ability for all-cause …

In 2005, the International Society for Heart and Lung Transplantation (ISHLT) Board of
Directors commissioned the development of the first International Listing Criteria for Heart …

Due to the aging and increasingly complex nature of our patients, frailty has become a high-
priority theme in cardiovascular medicine. Despite the recognition of frailty as a pivotal …

The last several years have seen increasing interest in understanding cachexia, muscle
wasting, and physical frailty across the broad spectrum of patients with cardiovascular …