Influence of maternal thyroid hormones during gestation on fetal brain development

NK Moog, S Entringer, C Heim, PD Wadhwa… - Neuroscience, 2017 - Elsevier
Thyroid hormones (THs) play an obligatory role in many fundamental processes underlying
brain development and maturation. The developing embryo/fetus is dependent on maternal …

Iodine as essential nutrient during the first 1000 days of life

I Velasco, SC Bath, MP Rayman - Nutrients, 2018 - mdpi.com
Iodine is an essential micronutrient incorporated into thyroid hormones. Although iodine
deficiency can lead to a broad spectrum of disorders throughout life, it is most critical in the …

The Na+/I Symporter (NIS): Mechanism and Medical Impact

C Portulano, M Paroder-Belenitsky… - Endocrine …, 2014 - academic.oup.com
Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Maternal hormonal milieu influence on fetal brain development

A Miranda, N Sousa - Brain and behavior, 2018 - Wiley Online Library
An adverse maternal hormonal environment during pregnancy can be associated with
abnormal brain growth. Subtle changes in fetal brain development have been observed …

The role of thyroid hormones for brain development and cognitive function

JF Rovet - Paediatric Thyroidology, 2014 - karger.com
Through its actions on regulatory genes that form, grow and sculpt the brain, thyroid
hormone (TH) is essential for human brain development. Although much of what we know …

Regulation of thyroid-disrupting chemicals to protect the developing brain

ME Gilbert, KL O'Shaughnessy, M Axelstad - Endocrinology, 2020 - academic.oup.com
Synthetic chemicals with endocrine disrupting properties are pervasive in the environment
and are present in the bodies of humans and wildlife. As thyroid hormones (THs) control …

Exposure to the widely used fungicide mancozeb causes thyroid hormone disruption in rat dams but no behavioral effects in the offspring

M Axelstad, J Boberg, C Nellemann… - Toxicological …, 2011 - academic.oup.com
The widely used fungicide mancozeb has been shown to cause hypothyroxinemia and other
adverse effects on the thyroid hormone system in adult experimental animals. In humans …

The impact of the micronutrient iodine in health and diseases

MC Opazo, I Coronado-Arrázola… - Critical reviews in …, 2022 - Taylor & Francis
Adequate iodine nutrition is crucial for all mammals by playing his starring role as a
component of thyroid hormones, which are key regulators of cellular processes for life such …

Microbial endocrinology: host–bacteria communication within the gut microbiome

S Sandrini, M Aldriwesh, M Alruways… - Journal of …, 2015 - joe.bioscientifica.com
Isolated maternal hypothyroxinemia (IMH) during pregnancy is defined as a low maternal T
4 in the absence of TSH elevation. As IMH is common, with a prevalence of 1–2% in iodine …

Management of endocrine disease: isolated maternal hypothyroxinemia during pregnancy: knowns and unknowns

C Dosiou, M Medici - European journal of endocrinology, 2017 - academic.oup.com
Isolated maternal hypothyroxinemia (IMH) during pregnancy is defined as a low maternal T4
in the absence of TSH elevation. As IMH is common, with a prevalence of 1–2% in iodine …