Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …

Maintaining a normal healthy immune defense system lowers the incidence and/or the
severity of symptoms and/or the duration of common cold (CC). Physical barriers and innate …

Immune responses in the CNS are common, despite its perception as a site of immune
privilege. These responses can be mediated by resident microglia and astrocytes, which are …

SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …

Glioblastoma (GBM) contains self-renewing GBM stem cells (GSC) potentially amenable to
immunologic targeting, but chimeric antigen receptor (CAR) T-cell therapy has demonstrated …

Coronaviruses are a family of enveloped, single-stranded, positive-strand RNA viruses
classified within the Nidovirales order. This coronavirus family consists of pathogens of …

Background More than 300 million people carry a diagnosis of asthma, with data to suggest
that they are at a higher risk for infection or adverse outcomes from severe acute respiratory …

Tissue resident memory (Trm) CD8 T cells represent a newly described memory T cell
population. We have previously characterized a population of Trm cells that persists within …

Alzheimer's disease is characterized by the combined presence of amyloid plaques and tau
pathology, the latter being correlated with the progression of clinical symptoms …

Several viruses infect the mammalian central nervous system (CNS), some with devastating
consequences, others resulting in chronic or persistent infections associated with little or no …