Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

Tumor-infiltrating myeloid cells (TIMs) are key regulators in tumor progression, but the
similarity and distinction of their fundamental properties across different tumors remain …

Recent findings have demonstrated that mitochondria can be transferred between cells to
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …

Heart failure represents a major cause of morbidity and mortality worldwide. Single-cell
transcriptomics have revolutionized our understanding of cell composition and associated …

The physiological processes of cell growth, proliferation, differentiation, and apoptosis are
closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has …

Over 200 million people suffer from osteoporosis worldwide. Individuals with osteoporosis
have increased rates of bone resorption while simultaneously having impaired …

The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
and “anatomical escape” characteristics threaten the effectiveness of current coronavirus …

Monocytes and macrophages are central players of the innate immune response and play a
pivotal role in the regulation of inflammation. Thereby, they actively participate in all phases …

Alzheimer's disease (AD) and dementia in general are age-related diseases with multiple
contributing factors, including brain inflammation. Microglia, and specifically those …