Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases
SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …
health and homeostasis. Although white adipose tissue and brown adipose tissue are …
The evolving view of thermogenic adipocytes—ontogeny, niche and function
The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …
reached pandemic levels. Central to the development of these metabolic disorders is …
Obesity and thyroid axis
K Walczak, L Sieminska - … journal of environmental research and public …, 2021 - mdpi.com
Development of obesity is primarily the result of imbalance between energy intake and
energy expenditure. Thyroid hormones influence energy expenditure by regulating cellular …
energy expenditure. Thyroid hormones influence energy expenditure by regulating cellular …
The role of thyroid hormone in metabolism and metabolic syndrome
PFS Teixeira, PB Dos Santos… - … in endocrinology and …, 2020 - journals.sagepub.com
Metabolic syndrome (MetS) and thyroid dysfunction are common in clinical practice. The
objectives of this review are to discuss some proposed mechanisms by which thyroid …
objectives of this review are to discuss some proposed mechanisms by which thyroid …
Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation
Current pharmacological therapies for treating obesity are of limited efficacy. Genetic
ablation or loss of function of AMP-activated protein kinase alpha 1 (AMPKα1) in …
ablation or loss of function of AMP-activated protein kinase alpha 1 (AMPKα1) in …
Thermogenesis in adipose tissue activated by thyroid hormone
WW Yau, PM Yen - International journal of molecular sciences, 2020 - mdpi.com
Thermogenesis is the production of heat that occurs in all warm-blooded animals. During
cold exposure, there is obligatory thermogenesis derived from body metabolism as well as …
cold exposure, there is obligatory thermogenesis derived from body metabolism as well as …
Signaling pathways regulating thermogenesis
C Tabuchi, HS Sul - Frontiers in endocrinology, 2021 - frontiersin.org
Obesity, an excess accumulation of white adipose tissue (WAT), has become a global
epidemic and is associated with complex diseases, such as type 2 diabetes and …
epidemic and is associated with complex diseases, such as type 2 diabetes and …
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …
Many ways to Rome: exercise, cold exposure and diet—do they all affect BAT activation and WAT browning in the same manner?
AK Scheel, L Espelage, A Chadt - International journal of molecular …, 2022 - mdpi.com
The discovery of functional brown adipose tissue (BAT) in adult humans and the possibility
to recruit beige cells with high thermogenic potential within white adipose tissue (WAT) …
to recruit beige cells with high thermogenic potential within white adipose tissue (WAT) …
Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis
NC Bal, M Periasamy - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Thermogenesis in endotherms relies on both shivering and non-shivering thermogenesis
(NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of …
(NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of …