Acute Kidney Injury in Patients with Cirrhosis | NEJM Skip to main content NEJM Group Follow
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Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …

The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

Effective immunosupression management is central to achieving optimal outcomes in liver
transplant recipients. Current immunosuppression regimens and agents are highly effective …

Abstract Background & Aims Renal clearance is the major elimination pathway for
sofosbuvir (SOF). We assessed the safety and efficacy of SOF‐containing regimens in …

Acute kidney injury (AKI) is common in patients with cirrhosis and associated with significant
mortality. The most common etiologies of AKI in this setting are prerenal azotemia (PRA) …

Renal failure, a challenging complication of cirrhosis, is one of the most important risk factors
for liver transplantation. In recent years, substantial progress has been made toward …

Acute kidney injury (AKI) is a common and devastating complication in patients with
cirrhosis. However, the definitions of AKI employed in studies involving patients with …

Kidney biomarkers appear to be useful in differential diagnosis between acute tubular
necrosis (ATN) and other types of acute kidney injury (AKI) in cirrhosis, particularly …