Rational design of polymeric micelles for targeted therapeutic delivery
Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
Role and therapeutic targeting strategies of neutrophil extracellular traps in inflammation
X Li, S Xiao, N Filipczak, SSK Yalamarty… - International Journal …, 2023 - Taylor & Francis
Neutrophil extracellular traps (NETs) are large DNA reticular structures secreted by
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …
NETosis: sculpting tumor metastasis and immunotherapy
Y Hu, H Wang, Y Liu - Immunological Reviews, 2024 - Wiley Online Library
The process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar
death modality of neutrophils, which was first observed as an immune response against …
death modality of neutrophils, which was first observed as an immune response against …
Neutrophil extracellular traps mediate deep vein thrombosis: from mechanism to therapy
M Yao, J Ma, D Wu, C Fang, Z Wang, T Guo… - Frontiers in …, 2023 - frontiersin.org
Deep venous thrombosis (DVT) is a part of venous thromboembolism (VTE) that clinically
manifests as swelling and pain in the lower limbs. The most serious clinical complication of …
manifests as swelling and pain in the lower limbs. The most serious clinical complication of …
Neutrophil extracellular traps in intracerebral hemorrhage: implications for pathogenesis and therapeutic targets
J Liu, S Zhang, Y Jing, W Zou - Metabolic Brain Disease, 2023 - Springer
Intracerebral hemorrhage is a common neurological disease, and its pathological
mechanism is complex. As the first recruited leukocyte subtype after intracerebral …
mechanism is complex. As the first recruited leukocyte subtype after intracerebral …
Manganese doped nanosystem for degrading neutrophil extracellular traps and improving chemotherapy efficiency to synergistically inhibit lung metastasis of breast …
Y Hao, X Li, Y Liu, D Liu, X Zhao, S Ji, H Chen… - Chemical Engineering …, 2023 - Elsevier
New treatment patterns have emerged by destroying neutrophil extracellular traps (NETs)
with DNase-1 to prevent tumor metastasis. However, the DNase-1 as a therapeutic agent …
with DNase-1 to prevent tumor metastasis. However, the DNase-1 as a therapeutic agent …
A Two-Pronged Delivery Strategy Disrupting Positive Feedback Loop of Neutrophil Extracellular Traps for Metastasis Suppression
J Kong, Y Deng, Y Xu, P Zhang, L Li, Y Huang - ACS nano, 2024 - ACS Publications
Neutrophil extracellular traps (NETs) severely affect tumor metastasis through a self-
perpetuating feedback loop involving two key steps:(1) mitochondrial aerobic respiration …
perpetuating feedback loop involving two key steps:(1) mitochondrial aerobic respiration …
Neutrophil Extracellular Traps in Tumors and Potential Use of Traditional Herbal Medicine Formulations for Its Regulation
X Li, L Hu, A Naeem, S Xiao, M Yang… - International Journal …, 2024 - Taylor & Francis
Neutrophil extracellular traps (NETs) are extracellular fibers composed of deoxyribonucleic
acid (DNA) and decorated proteins produced by neutrophils. Recently, NETs have been …
acid (DNA) and decorated proteins produced by neutrophils. Recently, NETs have been …
Imaging and Therapy of Tumors Based on Neutrophil Extracellular Traps
Y Hao, D Liu, K Wang, Q Liu, H Chen, S Ji… - Small …, 2024 - Wiley Online Library
Neutrophil extracellular traps (NETs) formed by neutrophils are netlike scaffolds that mainly
contain DNA and a variety of granule proteins. Many stimuli can lead to the NET formation …
contain DNA and a variety of granule proteins. Many stimuli can lead to the NET formation …
The semi-interpenetrating network hydrogel loaded with Oridonin and DNase-I on healing of chemoradiotherapy-induced oral mucositis
Y Pan, M Wang, P Wang, H Wei, X Wei, D Wang… - Biomaterials …, 2024 - pubs.rsc.org
Oral mucositis (OM) is a common side effect experienced by cancer patients undergoing
chemotherapy and/or radiotherapy. In this study, we developed a semi-interpenetrating …
chemotherapy and/or radiotherapy. In this study, we developed a semi-interpenetrating …