Background: Vitamin D is a secosteroid, which was initially known for its skeletal role;
however, in recent years, its functions in different organs have been increasingly …

The skin constitutes a formidable barrier against commensal and pathogenic bacteria, which
permanently and transiently colonise the skin, respectively. Commensal and pathogenic …

In this study, we developed a system for the transdermal delivery and controlled release of
the hydrophobic immunosuppressive drug rapamycin, foreseeing an application in psoriasis …

The pathogenetic mechanisms responsible for the induction of immune‐mediated disorders,
such as psoriasis, remain not well characterized. Molecular signaling pathways are not well …

Abstract Tyrosine kinase 2 (TYK2), a key part of the Janus kinase-signal transducer and
activator of transcription (JAK-STAT) pathway, plays an integral role in the differentiation and …

Although reduced natural killer (NK) cell levels have been reported consistently in patients
with coronary artery disease (CAD), the clinical significance and persistence of this immune …

Psoriasis is a common chronic inflammatory skin condition in which patients suffer from mild
to chronic plaque skin plaques. The disease manifests through an excessive inflammatory …

Head and neck cancers (HNCs) are known to present multiple factors likely to influence their
development. This review aims to provide a comprehensive overview of the current scientific …

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with different
variety of clinical manifestations. Natural killer T (NKT) cells are innate lymphocytes that play …

Objective To search for the immunological risk factors of Psoriatic arthritis (PsA) combined
with nonalcoholic fatty liver disease (NAFLD), development and assessment of predictive …