Oxidative stress is a pathological condition occurring due to an imbalance between the
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …

Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …

Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …

Cell-based medicine has made great advances in clinical diagnosis and therapy for various
refractory diseases, inducing a growing demand for cell preservation as support technology …

Fuchs' endothelial corneal dystrophy (FECD) is the most prominent reason for corneal-
endothelial transplantations across the globe. The disease pathophysiology manifests …

Irisin is an exercise-induced myokine that alleviates inflammation and obesity. The induction
of anti-inflammatory (M2) macrophage is facilitated for treatment of sepsis and associated …

Introduction Ischemic stroke is one of the leading causes of death worldwide. Recently,
neuroprotection is regarded as an important preventative and therapeutic strategy for …

The aim of the study was to investigate oxidative stress as well as cellular protein
accumulation in corneal diseases including keratoconus (KC), macular corneal dystrophy …

Juices, wine, coffee, and cocoa are rich sources of natural polyphenolic compounds that
have potent antioxidant activities proven by in vitro and in vivo studies. These polyphenolic …

Purpose: To investigate the impact of oxidative stress, which is a hallmark of Fuchs
dystrophy, on the barrier function of the corneal endothelial cells. Methods: Experiments …