[HTML][HTML] Improving diagnostic accuracy in food allergy

RX Foong, JA Dantzer, RA Wood, AF Santos - The Journal of Allergy and …, 2021 - Elsevier
The diagnosis of food allergy can have a major impact on the lives of patients and families,
imposing dietary restrictions and limitations on social activities. On the other hand …

[HTML][HTML] Cross-reactive epitopes and their role in food allergy

SD Kamath, M Bublin, K Kitamura, T Matsui, K Ito… - Journal of Allergy and …, 2023 - Elsevier
Allergenic cross-reactivity among food allergens complicates the diagnosis and
management of food allergy. This can result in many patients being sensitized (having …

The importance of the 2S albumins for allergenicity and cross-reactivity of peanuts, tree nuts, and sesame seeds

SC Dreskin, SJ Koppelman, S Andorf… - Journal of Allergy and …, 2021 - Elsevier
Allergies to peanuts, tree nuts, and sesame seeds are among the most important food-
related causes of anaphylaxis. Important clinical questions include: Why is there a variable …

Molecularly imprinted polymer as a synthetic antibody for the biorecognition of hazelnut Cor a 14-allergen

R Costa, J Costa, P Moreira, ATSC Brandao… - Analytica Chimica …, 2022 - Elsevier
Artificial receptors that mimic their natural biological counterparts have several advantages,
such as lower production costs and increased shelf-life stability/versatility, while overcoming …

Still SDAPing along: 20 years of the structural database of allergenic proteins

CH Schein, SS Negi, W Braun - Frontiers in Allergy, 2022 - frontiersin.org
The introduction of plant extracts to mitigate the symptoms of “hay fever”, about a century
ago, led to discoveries beginning sixty years ago on determining the sequences and …

IgE-Mediated food allergy: Current diagnostic modalities and novel biomarkers with robust potential

Q Xie, W Xue - Critical Reviews in Food Science and Nutrition, 2023 - Taylor & Francis
Food allergy (FA) is a serious public health issue afflicting millions of people globally, with
an estimated prevalence ranging from 1-10%. Management of FA is challenging due to …

Comparative analysis of allergenicity and predicted linear epitopes in α and β parvalbumin from turbot (Scophthalmus maximus)

Y Huang, Z Li, Y Wu, Y Li, S Pramod… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND Parvalbumin (PV) can be subdivided into two phylogenetic lineages, αPV
and βPV. The bony fish βPV is considered a major fish allergen. However, there is no …

Structure, immunogenicity, and IgE cross-reactivity among walnut and peanut vicilin-buried peptides

ACY Foo, JB Nesbit, SAY Gipson… - Journal of agricultural …, 2022 - ACS Publications
Vicilin-buried peptides (VBPs) from edible plants are derived from the N-terminal leader
sequences (LSs) of seed storage proteins. VBPs are defined by a common α-hairpin fold …

The effector function of allergens

S Hazebrouck, N Canon, SC Dreskin - Frontiers in Allergy, 2022 - frontiersin.org
Allergens are antigens that generate an IgE response (sensitization) in susceptible
individuals. The allergenicity of an allergen can be thought of in terms of its ability to …

[HTML][HTML] The updated Structural Database of Allergenic Proteins (SDAP 2.0) provides 3D models for allergens and incorporated bioinformatics tools

SS Negi, CH Schein, W Braun - Journal of Allergy and Clinical Immunology …, 2023 - Elsevier
Background Allergenic proteins can cause IgE-mediated adverse reactions in sensitized
individuals. Although the sequences of many allergenic proteins have been identified …