Cytokines and Chemokines in Mycobacterium tuberculosis Infection

R Domingo-Gonzalez, O Prince, A Cooper… - Microbiology …, 2016 - Am Soc Microbiol
Chemokines and cytokines are critical for initiating and coordinating the organized and
sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected …

[HTML][HTML] Overview of the mechanisms that may contribute to the non-redundant activities of interferon-inducible CXC chemokine receptor 3 ligands

M Metzemaekers, V Vanheule, R Janssens… - Frontiers in …, 2018 - frontiersin.org
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …

International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for …

F Bachelerie, A Ben-Baruch, AM Burkhardt… - Pharmacological …, 2014 - ASPET
Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Neutrophil trails guide influenza-specific CD8+ T cells in the airways

K Lim, YM Hyun, K Lambert-Emo, T Capece, S Bae… - Science, 2015 - science.org
INTRODUCTION Influenza virus infects the epithelial cells that line the respiratory tract.
Therefore, cytotoxic CD8+ T cells must traffic to this site to eliminate infected cells. The …

CXCR3 in T cell function

JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …

CXCR3 ligands: redundant, collaborative and antagonistic functions

JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …

Chemokines from a structural perspective

MC Miller, KH Mayo - International journal of molecular sciences, 2017 - mdpi.com
Chemokines are a family of small, highly conserved cytokines that mediate various
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …

The emerging role of CXCL10 in cancer

M Liu, S Guo, JK Stiles - Oncology letters, 2011 - spandidos-publications.com
The chemokine interferon-γ inducible protein 10 kDa (CXCL10) is a member of the CXC
chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 …

Gram-positive anaerobic cocci–commensals and opportunistic pathogens

EC Murphy, IM Frick - FEMS microbiology reviews, 2013 - academic.oup.com
Among the Gram-positive anaerobic bacteria associated with clinical infections, the Gram-
positive anaerobic cocci (GPAC) are the most prominent and account for approximately 25 …

Chemokines and their receptors: drug targets in immunity and inflammation

A Viola, AD Luster - Annu. Rev. Pharmacol. Toxicol., 2008 - annualreviews.org
The chemokine system coordinates leukocyte migration in immunity and inflammation and is
implicated in the pathogenesis of many human diseases. Although several successful …