DNA as a biomaterial has evoked great interest as a potential platform for therapeutics and
diagnostics and as hydrogel scaffolds due to the relative ease of programming its robust and …

Contamination of samples with DNA is still a major problem in microbiology laboratories,
despite the wide acceptance of PCR and other amplification techniques for the detection of …

The BLAST algorithm was developed as a way to perform DNA and protein sequence
similarity searches by an algorithm that is faster than FASTA but considered to be equally as …

Ultraviolet (UV) radiation is a leading external hazard to the integrity of DNA. Exposure to UV
radiation triggers a cascade of chemical reactions, and many molecular products …

MANY plant genes that respond to environmental and developmental changes are
regulated by jasmonic acid, which is derived from linolenic acid via the octadecanoid …

We have determined the distribution of the major UV-induced photoproducts in nucleosome
core DNA using the 3'----5'exonuclease activity of T4 DNA polymerase, which has been …

It is well established that exposure to solar UVB (290-320 nm) gives rise to mutations in
oncogenes and tumor suppressor genes that initiate the molecular cascade toward skin …

The rate of excision repair of UV-induced pyrimidine dimers (PDs) was measured at specific
sites in each strand of a yeast minichromosome containing an active gene (URA3), a …

Nucleotide excision repair (NER) is one of the major cellular pathways that removes bulky
DNA adducts and helix-distorting lesions. The biological consequences of defective NER in …

Cyclobutane pyrimidine dimers (CPDs) are the major products of DNA produced by direct
absorption of UV light, and result in C to T mutations linked to human skin cancers. Most …