The roles of androgens in humans: biology, metabolic regulation and health
M Alemany - International journal of molecular sciences, 2022 - mdpi.com
Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …
play varied functional roles, such as the control of metabolic energy fate and partition, the …
The hypothalamus-pituitary-gonad axis: tales of mice and men
A Kaprara, IT Huhtaniemi - Metabolism, 2018 - Elsevier
Reproduction is controlled by the hypothalamic-pituitary-gonadal (HPG) axis. Gonadotropin-
releasing hormone (GnRH) neurons play a central role in this axis through production of …
releasing hormone (GnRH) neurons play a central role in this axis through production of …
Determinants of menarche
O Karapanou, A Papadimitriou - Reproductive Biology and Endocrinology, 2010 - Springer
Menarche is a milestone in a woman's life as it denotes the start of reproductive capacity.
Aim of this report is to review the recent developments and the current knowledge in the …
Aim of this report is to review the recent developments and the current knowledge in the …
Homeostatic control of the thyroid–pituitary axis: perspectives for diagnosis and treatment
R Hoermann, JEM Midgley, R Larisch… - Frontiers in …, 2015 - frontiersin.org
The long-held concept of a proportional negative feedback control between the thyroid and
pituitary glands requires reconsideration in the light of more recent studies. Homeostatic …
pituitary glands requires reconsideration in the light of more recent studies. Homeostatic …
Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men
JT George, JD Veldhuis, AK Roseweir… - The Journal of …, 2011 - academic.oup.com
Abstract Context: Kisspeptins stimulate GnRH and thus gonadotropin secretion. Kisspeptin-
10 is the minimal kisspeptin sequence with full intrinsic bioactivity, but it has not been …
10 is the minimal kisspeptin sequence with full intrinsic bioactivity, but it has not been …
Meta-Analysis of Heifer Traits Identified Reproductive Pathways in Bos indicus Cattle
MS Tahir, LR Porto-Neto, C Gondro, OB Shittu… - Genes, 2021 - mdpi.com
Fertility traits measured early in life define the reproductive potential of heifers. Knowledge of
genetics and biology can help devise genomic selection methods to improve heifer fertility …
genetics and biology can help devise genomic selection methods to improve heifer fertility …
Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain
GnRH signaling regulates reproductive physiology in vertebrates via the hypothalamic-
pituitary-gonadal axis. In addition, GnRH signaling has been postulated to act on the brain …
pituitary-gonadal axis. In addition, GnRH signaling has been postulated to act on the brain …
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice
J Roa, M Ruiz-Cruz, F Ruiz-Pino, R Onieva… - Nature …, 2022 - nature.com
Kiss1 neurons, producing kisspeptins, are essential for puberty and fertility, but their
molecular regulatory mechanisms remain unfolded. Here, we report that congenital ablation …
molecular regulatory mechanisms remain unfolded. Here, we report that congenital ablation …
Linking stress and infertility: a novel role for ghrelin
L Sominsky, DM Hodgson, EA McLaughlin… - Endocrine …, 2017 - academic.oup.com
Infertility affects a remarkable one in four couples in developing countries. Psychological
stress is a ubiquitous facet of life, and although stress affects us all at some point, prolonged …
stress is a ubiquitous facet of life, and although stress affects us all at some point, prolonged …
Puberty in the female and its disorders
RL Rosenfield, DW Cooke, S Radovick - Sperling Pediatric Endocrinology, 2021 - Elsevier
This chapter begins with a basic science update on the development of the female
reproductive system. This starts with sections on maturation of the neuroendocrine-ovarian …
reproductive system. This starts with sections on maturation of the neuroendocrine-ovarian …