Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer

S Pordel, M Khorrami, F Saadatpour, D Rezaee… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

Pembrolizumab monotherapy for the treatment of high-risk non-muscle-invasive bladder cancer unresponsive to BCG (KEYNOTE-057): an open-label, single-arm …

AV Balar, AM Kamat, GS Kulkarni, EM Uchio… - The Lancet …, 2021 - thelancet.com
Background Standard treatment for high-risk non-muscle-invasive bladder cancer is
transurethral resection of bladder tumour followed by intravesical BCG immunotherapy …

miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review

MT Di Martino, M Arbitrio, D Caracciolo… - … Therapy-Nucleic Acids, 2022 - cell.com
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …

[HTML][HTML] The impact of biological sex on diseases of the urinary tract

L Deltourbe, LL Mariano, TN Hreha, DA Hunstad… - Mucosal …, 2022 - Elsevier
Biological sex, being female or male, broadly influences diverse immune phenotypes,
including immune responses to diseases at mucosal surfaces. Sex hormones, sex …

CD8+ T effector and immune checkpoint signatures predict prognosis and responsiveness to immunotherapy in bladder cancer

X Chen, R Xu, D He, Y Zhang, H Chen, Y Zhu… - Oncogene, 2021 - nature.com
Immune-checkpoint blockade (ICB) has been routinely implemented to treat bladder cancer;
however, most patients have little or no clinical benefit. In this study, 348 pretreated …

The impact of vitamin D on cancer: A mini review

G Seraphin, S Rieger, M Hewison… - The Journal of steroid …, 2023 - Elsevier
In this review, we summarize the most recent advances in vitamin D cancer research to
provide molecular clarity, as well as its translational trajectory across the cancer landscape …

Antitumor, anti-inflammatory and antiallergic effects of Agaricus blazei mushroom extract and the related medicinal basidiomycetes mushrooms, Hericium erinaceus …

G Hetland, JM Tangen, F Mahmood, MR Mirlashari… - Nutrients, 2020 - mdpi.com
Since the 1980s, medicinal effects have been documented in scientific studies with the
related Basidiomycota mushrooms Agaricus blazei Murill (AbM), Hericium erinaceus (HE) …

Tumor‐derived exosomal BCYRN1 activates WNT5A/VEGF‐C/VEGFR3 feedforward loop to drive lymphatic metastasis of bladder cancer

H Zheng, C Chen, Y Luo, M Yu, W He… - Clinical and …, 2021 - Wiley Online Library
Background Patients with lymph node (LN) metastatic bladder cancer (BCa) present with
extremely poor prognosis. BCa‐derived exosomes function as crucial bioactive cargo …

Estimating national exposures and potential bladder cancer cases associated with chlorination DBPs in US drinking water

RJ Weisman, A Heinrich, F Letkiewicz… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Disinfection byproducts (DBPs) in public water systems (PWS) are an
unintended consequence resulting from reactions between mostly chlorine-based …